Tumor infiltrating Foxp3+ regulatory T‐cells are associated with recurrence in pathologic stage I NSCLC patients

BACKGROUND. Early stage lung cancer has a variable prognosis, and there are currently no markers that predict which patients will recur. This study examined the relation between tumor‐regulatory T (Treg) cells and total tumor‐infiltrating T‐cell lymphocytes (TIL) to determine whether they correlated...

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Veröffentlicht in:	Cancer 2006-12, Vol.107 (12), p.2866-2872
Hauptverfasser:	Petersen, Rebecca P., Campa, Michael J., Sperlazza, Justin, Conlon, Debbi, Joshi, Mary‐Beth, Harpole, David H., Patz, Edward F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Non-Small-Cell Lung - immunology Carcinoma, Non-Small-Cell Lung - pathology CD3 Complex - analysis Forkhead Transcription Factors - analysis Humans immunohistochemistry lung cancer Lung Neoplasms - diagnosis Lung Neoplasms - immunology Lung Neoplasms - pathology Lymphocytes, Tumor-Infiltrating - chemistry Lymphocytes, Tumor-Infiltrating - immunology Medical sciences Neoplasm Recurrence, Local - diagnosis Neoplasm Recurrence, Local - immunology Neoplasm Recurrence, Local - pathology Neoplasm Staging Pneumology Prognosis regulatory T cells T-Lymphocytes, Regulatory - chemistry T-Lymphocytes, Regulatory - immunology Tumors Tumors of the respiratory system and mediastinum
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