Cryptococcus gattii infection causing fulminant intracranial hypertension

Cryptococcus neoformans variety gattii (C. gattii) causes infection in predominantly immunocompetent individuals. The majority of cases present with headache due to meningitis and its natural history normally follows an indolent course. We report a fatal case of fulminant cryptococcaemia culminating...

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Veröffentlicht in:British journal of anaesthesia : BJA 2007-10, Vol.99 (4), p.528-531
Hauptverfasser: Bromilow, J., Corcoran, T.
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Corcoran, T.
description Cryptococcus neoformans variety gattii (C. gattii) causes infection in predominantly immunocompetent individuals. The majority of cases present with headache due to meningitis and its natural history normally follows an indolent course. We report a fatal case of fulminant cryptococcaemia culminating in severe intracranial hypertension due to C. gattii. Such cases of fulminant disease are rare and highlight a number of important therapeutic and diagnostic considerations. We discuss the atypical nature of this patient’s illness, the major complications of C. gattii meningitis and the role of computed tomography (CT) in preventing serious sequelae from lumbar puncture. The management of intracranial hypertension (ICH) in critically ill patients is also reviewed.
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subjects Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
brain, intracranial pressure
coma, aetiology
Cryptococcus neoformans
cryptococcus, physiology
Fatal Outcome
Humans
intracranial hypertension
Intracranial Hypertension - diagnostic imaging
Intracranial Hypertension - microbiology
Male
Medical sciences
meningitis, cryptococcal
Meningitis, Cryptococcal - complications
Meningitis, Cryptococcal - diagnostic imaging
Middle Aged
Tomography, X-Ray Computed
title Cryptococcus gattii infection causing fulminant intracranial hypertension
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