Peptides by Extension at the N- or C-terminii of Lysine

Dipeptides 3a–g, (3a + 3a′), (3d + 3d′), (3l + 3l′)a and tripeptides 6a–e, (6b + 6b′), (6e + 6e′) incorporating Zε‐Lys were prepared in high yields (70–95%) and enantiopurity (≥97%) in partially aqueous acetonitrile solution by coupling using (i) Zε‐Lys with N‐(Z‐ and Fmoc‐aminoacyl)benzotriazoles 1...

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Veröffentlicht in:	Chemical biology & drug design 2006-12, Vol.68 (6), p.326-333
Hauptverfasser:	Katritzky, Alan R., Meher, Geeta, Angrish, Parul
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetonitriles - chemistry acylating reagent benzotriazole Dipeptides - chemical synthesis Dipeptides - chemistry lysine Lysine - chemistry N-(protected-α-aminoacyl)benzotriazole Oligopeptides - chemical synthesis Oligopeptides - chemistry peptide coupling Solutions - chemistry Stereoisomerism
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