Mutation of the Apc1 homologue shattered disrupts normal eye development by disrupting G1 cell cycle arrest and progression through mitosis

The shattered1 (shtd1) mutation disrupts Drosophila compound eye structure. In this report, we show that the shtd1 eye defects are due to a failure to establish and maintain G1 arrest in the morphogenetic furrow (MF) and a defect in progression through mitosis. The observed cell cycle defects were c...

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Veröffentlicht in:Developmental biology 2007-09, Vol.309 (2), p.222-235
Hauptverfasser: Tanaka-Matakatsu, Miho, Thomas, Barbara J., Du, Wei
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Sprache:eng
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