Breast Cancer Resistance Protein (Bcrp1/Abcg2) in Mouse Placenta and Yolk Sac: Ontogeny and its Regulation by Progesterone

Abstract Breast Cancer Resistance Protein (BCRP), a recently-discovered transporter belonging to ABC superfamily, is highly expressed within the labyrinth of the placenta, the primary site of exchange between the maternal and fetal circulation. It has been proposed to function as an efflux pump prot...

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Veröffentlicht in:	Placenta (Eastbourne) 2007-10, Vol.28 (10), p.1073-1081
Hauptverfasser:	Kalabis, G.M, Petropoulos, S, Gibb, W, Matthews, S.G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP Binding Cassette Transporter, Sub-Family G, Member 2 ATP-Binding Cassette Transporters - physiology Biological and medical sciences Breast cancer resistance protein Embryology: invertebrates and vertebrates. Teratology Endocrinology Female Fetal protection Fundamental and applied biological sciences. Psychology Internal Medicine Mice Mouse placenta Obstetrics and Gynecology Placenta - drug effects Placenta - metabolism Pregnancy Progesterone Progesterone - blood Progesterone - pharmacology RNA, Messenger - metabolism Yolk sac Yolk Sac - drug effects Yolk Sac - metabolism
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