Two therapeutic challenges: periocular and genital vitiligo in children successfully treated with pimecrolimus cream
Vitiligo is characterized by the selective destruction of melanocytes resulting in patches of skin depigmentation. Vitiligo is a therapeutic challenge. Eyebrows, eyelids and genital vitiligo are a therapeutic dilemma, especially in children. The possible side effects of topical corticosteroids and t...
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| Veröffentlicht in: | International journal of dermatology 2007-09, Vol.46 (9), p.986-989 |
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| container_title | International journal of dermatology |
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| creator | Souza Leite, Rubens Marcelo Craveiro Leite, Adriana Aragão |
| description | Vitiligo is characterized by the selective destruction of melanocytes resulting in patches of skin depigmentation. Vitiligo is a therapeutic challenge. Eyebrows, eyelids and genital vitiligo are a therapeutic dilemma, especially in children. The possible side effects of topical corticosteroids and the difficulties for choosing any other adequate treatment option are a major concern. We present two children, one with vitiligo of the eyelids and the other with genital vitiligo, both treated with pimecrolimus 1% cream with almost full repigmentation of the lesions, showing pimecrolimus could be an adequate option for the treatment of vitiligo for these special vitiligo areas in children. |
| doi_str_mv | 10.1111/j.1365-4632.2007.03282.x |
| format | Article |
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Vitiligo is a therapeutic challenge. Eyebrows, eyelids and genital vitiligo are a therapeutic dilemma, especially in children. The possible side effects of topical corticosteroids and the difficulties for choosing any other adequate treatment option are a major concern. We present two children, one with vitiligo of the eyelids and the other with genital vitiligo, both treated with pimecrolimus 1% cream with almost full repigmentation of the lesions, showing pimecrolimus could be an adequate option for the treatment of vitiligo for these special vitiligo areas in children.</description><identifier>ISSN: 0011-9059</identifier><identifier>EISSN: 1365-4632</identifier><identifier>DOI: 10.1111/j.1365-4632.2007.03282.x</identifier><identifier>PMID: 17822508</identifier><identifier>CODEN: IJDEBB</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Administration, Topical ; Biological and medical sciences ; Child ; Dermatology ; Eyelids - pathology ; General aspects ; Humans ; Immunosuppressive Agents - therapeutic use ; Male ; Medical sciences ; Penis - pathology ; Pigmentary diseases of the skin ; Remission Induction ; Skin - pathology ; Tacrolimus - analogs & derivatives ; Tacrolimus - therapeutic use ; Vitiligo - drug therapy ; Vitiligo - pathology</subject><ispartof>International journal of dermatology, 2007-09, Vol.46 (9), p.986-989</ispartof><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4352-a9a4e4647bc21748ccfa43bcf1a7024db9f42771778186c3f86160236364179e3</citedby><cites>FETCH-LOGICAL-c4352-a9a4e4647bc21748ccfa43bcf1a7024db9f42771778186c3f86160236364179e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-4632.2007.03282.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-4632.2007.03282.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19055148$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17822508$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Souza Leite, Rubens Marcelo</creatorcontrib><creatorcontrib>Craveiro Leite, Adriana Aragão</creatorcontrib><title>Two therapeutic challenges: periocular and genital vitiligo in children successfully treated with pimecrolimus cream</title><title>International journal of dermatology</title><addtitle>Int J Dermatol</addtitle><description>Vitiligo is characterized by the selective destruction of melanocytes resulting in patches of skin depigmentation. Vitiligo is a therapeutic challenge. Eyebrows, eyelids and genital vitiligo are a therapeutic dilemma, especially in children. The possible side effects of topical corticosteroids and the difficulties for choosing any other adequate treatment option are a major concern. 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| ispartof | International journal of dermatology, 2007-09, Vol.46 (9), p.986-989 |
| issn | 0011-9059 1365-4632 |
| language | eng |
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| source | Wiley Online Library - AutoHoldings Journals; MEDLINE |
| subjects | Administration, Topical Biological and medical sciences Child Dermatology Eyelids - pathology General aspects Humans Immunosuppressive Agents - therapeutic use Male Medical sciences Penis - pathology Pigmentary diseases of the skin Remission Induction Skin - pathology Tacrolimus - analogs & derivatives Tacrolimus - therapeutic use Vitiligo - drug therapy Vitiligo - pathology |
| title | Two therapeutic challenges: periocular and genital vitiligo in children successfully treated with pimecrolimus cream |
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