Ca2+ ion accumulation precedes formation of O2. in isolated brain mitochondria

The relationship between mitochondrial Ca2+ accumulation and reactive oxygen species formation is studied by means of fast kinetics with fluorescence detection. Succinate or elevated [Na+] and [Ca2+] provided alternative conditions for induction of reactive oxygen species in isolated rat cerebrocort...

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Veröffentlicht in:	Neuroreport 2006-11, Vol.17 (17), p.1767-1771
Hauptverfasser:	SZARICS, Eva, KOVACS, Richard, HAJOS, Ferenc, KARDOS, Julianna
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry and metabolism Biological and medical sciences Brain - ultrastructure Calcium - metabolism Central nervous system Fundamental and applied biological sciences. Psychology Microscopy, Electron, Transmission - methods Mitochondria - metabolism Mitochondria - ultrastructure Oxygen - metabolism Rats Reactive Oxygen Species - metabolism Sodium-Calcium Exchanger - metabolism Superoxide Dismutase - metabolism Time Factors Vertebrates: nervous system and sense organs
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