Feasibility of multiple-mouse dynamic contrast-enhanced MRI

Dynamic contrast‐enhanced (DCE‐) MRI is often used to evaluate the response to experimental antiangiogenic therapies in small animal models of cancer. Unfortunately, DCE‐MRI studies often require a substantial investment of both time and money to achieve the desired level of statistical significance...

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Veröffentlicht in:	Magnetic resonance in medicine 2007-09, Vol.58 (3), p.610-615
Hauptverfasser:	Ramirez, Marc S., Ragan, Dustin K., Kundra, Vikas, Bankson, James A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Contrast Media - pharmacokinetics DCE-MRI Disease Models, Animal Equipment Design Feasibility Studies Fibrosarcoma - pathology Gadolinium DTPA - pharmacokinetics Gd-DTPA Image Enhancement - instrumentation Image Enhancement - methods Injections, Subcutaneous Magnetic Resonance Imaging - instrumentation Magnetic Resonance Imaging - methods Mice Mice, Nude multiple-mouse MRI Neoplasm Transplantation parallel imaging Time Factors
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