Successful graft patency after factor VIIa use for bleeding in coronary artery surgery: an unusual complication of a coronary artery bypass surgery
There is a growing literature regarding the use of recombinant activated factor VII (rFVIIa) (NovoSeven, NovoNordisk, Copenhagen, Denmark) to control refractory hemorrhage after cardiopulmonary bypass in cardiac surgery. This supporting evidence is mostly documented as case reports on patients, of w...
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| Veröffentlicht in: | Journal of cardiac surgery 2007-09, Vol.22 (5), p.424-427 |
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| container_end_page | 427 |
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| container_issue | 5 |
| container_start_page | 424 |
| container_title | Journal of cardiac surgery |
| container_volume | 22 |
| creator | Wahed, Shajahan Karagounis, Apostolos P Niranjan, Gunaratnam Kanagasabay, Robin |
| description | There is a growing literature regarding the use of recombinant activated factor VII (rFVIIa) (NovoSeven, NovoNordisk, Copenhagen, Denmark) to control refractory hemorrhage after cardiopulmonary bypass in cardiac surgery. This supporting evidence is mostly documented as case reports on patients, of which only six involve coronary artery grafting. We present our experience of a patient undergoing coronary artery bypass grafting, who suffered an anaphylactic reaction to protamine preventing safe reversal of systemic heparinization. Subsequent management of postoperative bleeding was successfully achieved only after rFVIIa administration. |
| doi_str_mv | 10.1111/j.1540-8191.2007.00440.x |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0886-0440 |
| ispartof | Journal of cardiac surgery, 2007-09, Vol.22 (5), p.424-427 |
| issn | 0886-0440 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68242013 |
| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Aged Coronary Artery Bypass - adverse effects Factor VII - therapeutic use Factor VIIa Hemostasis, Surgical Humans Male Postoperative Complications - drug therapy Postoperative Hemorrhage - drug therapy Postoperative Hemorrhage - etiology Recombinant Proteins - therapeutic use Treatment Outcome Vascular Patency |
| title | Successful graft patency after factor VIIa use for bleeding in coronary artery surgery: an unusual complication of a coronary artery bypass surgery |
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