Field evaluation of four novel enzyme immunoassays for Chagas' disease in Venezuela blood banks: comparison of assays using fixed-epimastigotes, fixed-trypomastigotes or trypomastigote excreted-secreted antigens from two Trypanosoma cruzi strains

summary Many serological tests have been developed for the diagnosis of Chagas’ disease, but few have been subjected to a rigorous field evaluation. We have recently described several novel enzyme immunoassays (EIAs) based on fixed‐whole organisms or trypomastigote excretory–secretory antigens (TESA...

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Veröffentlicht in:	Transfusion medicine (Oxford, England) England), 2006-12, Vol.16 (6), p.419-431
Hauptverfasser:	Berrizbeitia, M., Ndao, M., Bubis, J., Gottschalk, M., Aché, A., Lacouture, S., Medina, M., Ward, B. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Antibodies, Protozoan - isolation & purification Antigens, Protozoan - analysis Antigens, Protozoan - immunology Blood Banks - standards Chagas Disease - diagnosis Chagas' disease Female Humans Immunoenzyme Techniques - methods Male Middle Aged ROC Curve Serologic Tests - methods serological diagnosis Transfusion Reaction Trypanosoma cruzi Trypanosoma cruzi - immunology trypomastigote secreted-excreted antigens
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