Enantioselective [3 + 2]-Cycloadditions Catalyzed by a Protected, Multifunctional Phosphine-Containing α-Amino Acid

Catalytic asymmetric [3 + 2]-cycloaddition reactions between α-allenic esters and enones are presented. We have found that a simple phosphine-containing protected α-amino acid derivative is capable of promoting such cycloadditions in high yields with significant levels of regioselectivity and enanti...

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Veröffentlicht in:	Journal of the American Chemical Society 2007-09, Vol.129 (36), p.10988-10989
Hauptverfasser:	Cowen, Bryan J, Miller, Scott J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - chemistry Catalysis Esters - chemical synthesis Ketones - chemical synthesis Molecular Structure Phosphines - chemistry
Online-Zugang:	Volltext
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