Comparison of the Innofluor® certican assay with HPLC-UV for the determination of everolimus concentrations in heart transplantation

Therapeutic monitoring of everolimus with chromatographic methods (HPLC) enabled effective immunosuppression while limiting the incidence of drug-related adverse events. A fluorescence polarization immunoassay (FPIA) has been recently developed for the assessment of everolimus levels. The present st...

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Veröffentlicht in:	Clinical biochemistry 2006-12, Vol.39 (12), p.1152-1159
Hauptverfasser:	Baldelli, Sara, Crippa, Alberto, Gabrieli, Roberta, Fiocchi, Roberto, Perico, Norberto, Merlini, Simona, Ottomano, Cosimo, Cattaneo, Dario
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatography, High Pressure Liquid - methods Cross Reactions Everolimus Fluorescence Polarization Immunoassay - methods Heart Transplantation HPLC Immunoassay Method comparison Reagent Kits, Diagnostic - standards Sirolimus Sirolimus - analogs & derivatives Sirolimus - blood Sirolimus - therapeutic use Ultraviolet Rays
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