Detection of TMPRSS2-ERG Fusion Transcripts and Prostate Cancer Antigen 3 in Urinary Sediments May Improve Diagnosis of Prostate Cancer

Purpose: Early detection of prostate cancer can increase the curative success rate for prostate cancer. We studied the diagnostic usefulness of TMPRSS2-ERG fusion transcripts as well as the combination of prostate cancer antigen 3 (PCA3) RNA and TMPRSS2-ERG fusion transcripts in urinary sediments af...

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Veröffentlicht in:	Clinical cancer research 2007-09, Vol.13 (17), p.5103-5108
Hauptverfasser:	HESSELS, Daphne, SMIT, Frank P, VERHAEGH, Gerald W, WITJES, J. Alfred, CORNET, Erik B, SCHALKEN, Jack A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm - urine Antineoplastic agents Biological and medical sciences Biomarkers, Tumor gene fusions Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Medical sciences Nephrology. Urinary tract diseases Oncogene Proteins, Fusion - genetics PCA3 Pharmacology. Drug treatments Prognosis prostate cancer Prostatic Neoplasms - diagnosis Prostatic Neoplasms - mortality Prostatic Neoplasms - urine Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - urine TMPRSS2-ERG Tumors Tumors of the urinary system Urinary tract. Prostate gland urine
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