Troponin I Levels in Patients with Preeclampsia
Abstract Introduction Preeclampsia involves a diffuse inflammatory state and elevated levels of troponins in patients with preeclampsia have been anecdotally reported. It is, however, unknown whether it is attributable to the preeclampsia. Objective We sought to determine the troponin I levels at th...
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| Veröffentlicht in: | The American journal of medicine 2007-09, Vol.120 (9), p.819.e13-819.e14 |
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| creator | Joyal, Dominique, MD Leya, Ferdinand, MD Koh, Megan, MD Besinger, Richard, MD Ramana, Ravi, DO Kahn, Steven, PhD Jeske, Walter, PhD Lewis, Bruce, MD Steen, Lowell, MD Mestril, Ruben, PhD Arab, Dinesh, MD |
| description | Abstract Introduction Preeclampsia involves a diffuse inflammatory state and elevated levels of troponins in patients with preeclampsia have been anecdotally reported. It is, however, unknown whether it is attributable to the preeclampsia. Objective We sought to determine the troponin I levels at the time of delivery in pregnant women with and without preeclampsia. Methods Plasma samples were obtained at the time of delivery and serum troponin I was measured by ELISA method. Results Thirty-nine women were included (20 with preeclampsia and 19 without). Mean troponin I level was 0.008 ng/mL in patients with preeclampsia and 0.01 ng/mL in controls ( P =.59). The highest troponin I level was 0.04 ng/mL for both patients with and without preeclampsia. Conclusions Preeclampsia was not associated with a rise in troponin I levels in our study. Patients with preeclampsia and elevated troponin levels should have further cardiac investigations. |
| doi_str_mv | 10.1016/j.amjmed.2006.05.068 |
| format | Article |
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It is, however, unknown whether it is attributable to the preeclampsia. Objective We sought to determine the troponin I levels at the time of delivery in pregnant women with and without preeclampsia. Methods Plasma samples were obtained at the time of delivery and serum troponin I was measured by ELISA method. Results Thirty-nine women were included (20 with preeclampsia and 19 without). Mean troponin I level was 0.008 ng/mL in patients with preeclampsia and 0.01 ng/mL in controls ( P =.59). The highest troponin I level was 0.04 ng/mL for both patients with and without preeclampsia. Conclusions Preeclampsia was not associated with a rise in troponin I levels in our study. Patients with preeclampsia and elevated troponin levels should have further cardiac investigations.</description><identifier>ISSN: 0002-9343</identifier><identifier>EISSN: 1555-7162</identifier><identifier>DOI: 10.1016/j.amjmed.2006.05.068</identifier><identifier>PMID: 17765054</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Endothelium, Vascular - physiopathology ; Female ; Humans ; Internal Medicine ; Pre-Eclampsia - blood ; Pre-Eclampsia - physiopathology ; preeclampsia ; Pregnancy ; Pregnancy Trimester, Third ; Troponin ; Troponin I - blood</subject><ispartof>The American journal of medicine, 2007-09, Vol.120 (9), p.819.e13-819.e14</ispartof><rights>Elsevier Inc.</rights><rights>2007 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-9c67de1aa7afdd0cbcb87dba5aa504f8a96424cb33d81d6f560b50c92130ddd53</citedby><cites>FETCH-LOGICAL-c415t-9c67de1aa7afdd0cbcb87dba5aa504f8a96424cb33d81d6f560b50c92130ddd53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002934306008977$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17765054$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Joyal, Dominique, MD</creatorcontrib><creatorcontrib>Leya, Ferdinand, MD</creatorcontrib><creatorcontrib>Koh, Megan, MD</creatorcontrib><creatorcontrib>Besinger, Richard, MD</creatorcontrib><creatorcontrib>Ramana, Ravi, DO</creatorcontrib><creatorcontrib>Kahn, Steven, PhD</creatorcontrib><creatorcontrib>Jeske, Walter, PhD</creatorcontrib><creatorcontrib>Lewis, Bruce, MD</creatorcontrib><creatorcontrib>Steen, Lowell, MD</creatorcontrib><creatorcontrib>Mestril, Ruben, PhD</creatorcontrib><creatorcontrib>Arab, Dinesh, MD</creatorcontrib><title>Troponin I Levels in Patients with Preeclampsia</title><title>The American journal of medicine</title><addtitle>Am J Med</addtitle><description>Abstract Introduction Preeclampsia involves a diffuse inflammatory state and elevated levels of troponins in patients with preeclampsia have been anecdotally reported. It is, however, unknown whether it is attributable to the preeclampsia. Objective We sought to determine the troponin I levels at the time of delivery in pregnant women with and without preeclampsia. Methods Plasma samples were obtained at the time of delivery and serum troponin I was measured by ELISA method. Results Thirty-nine women were included (20 with preeclampsia and 19 without). Mean troponin I level was 0.008 ng/mL in patients with preeclampsia and 0.01 ng/mL in controls ( P =.59). The highest troponin I level was 0.04 ng/mL for both patients with and without preeclampsia. Conclusions Preeclampsia was not associated with a rise in troponin I levels in our study. Patients with preeclampsia and elevated troponin levels should have further cardiac investigations.</description><subject>Adult</subject><subject>Endothelium, Vascular - physiopathology</subject><subject>Female</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Pre-Eclampsia - blood</subject><subject>Pre-Eclampsia - physiopathology</subject><subject>preeclampsia</subject><subject>Pregnancy</subject><subject>Pregnancy Trimester, Third</subject><subject>Troponin</subject><subject>Troponin I - blood</subject><issn>0002-9343</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1LxDAQhoMouq7-A5GevLU7SZu0vQgifsGCC-o5pMkUU_uxJt0V_70pu3jw4mlmmHfegecl5IJCQoGKRZOorunQJAxAJMATEMUBmVHOeZxTwQ7JDABYXKZZekJOvW_CCCUXx-SE5rngwLMZWby6YT30to-eoiVusfVR6FdqtNiPPvqy43u0coi6Vd3aW3VGjmrVejzf1zl5u797vX2Ml88PT7c3y1hnlI9xqUVukCqVq9oY0JWuitxUiivFIasLVYqMZbpKU1NQI2ouoOKgS0ZTMMbwdE6udr5rN3xu0I-ys15j26oeh42XomCs5CkLwmwn1G7w3mEt1852yn1LCnICJRu5AyUnUBK4DKDC2eXef1NNu9-jPZkguN4JAhLcWnTS68BEo7EO9SjNYP_78NdAt7a3WrUf-I2-GTauDwQllZ5JkC9TWFNWIACKMs_TH3HUj8I</recordid><startdate>20070901</startdate><enddate>20070901</enddate><creator>Joyal, Dominique, MD</creator><creator>Leya, Ferdinand, MD</creator><creator>Koh, Megan, MD</creator><creator>Besinger, Richard, MD</creator><creator>Ramana, Ravi, DO</creator><creator>Kahn, Steven, PhD</creator><creator>Jeske, Walter, PhD</creator><creator>Lewis, Bruce, MD</creator><creator>Steen, Lowell, MD</creator><creator>Mestril, Ruben, PhD</creator><creator>Arab, Dinesh, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070901</creationdate><title>Troponin I Levels in Patients with Preeclampsia</title><author>Joyal, Dominique, MD ; Leya, Ferdinand, MD ; Koh, Megan, MD ; Besinger, Richard, MD ; Ramana, Ravi, DO ; Kahn, Steven, PhD ; Jeske, Walter, PhD ; Lewis, Bruce, MD ; Steen, Lowell, MD ; Mestril, Ruben, PhD ; Arab, Dinesh, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-9c67de1aa7afdd0cbcb87dba5aa504f8a96424cb33d81d6f560b50c92130ddd53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Endothelium, Vascular - physiopathology</topic><topic>Female</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Pre-Eclampsia - blood</topic><topic>Pre-Eclampsia - physiopathology</topic><topic>preeclampsia</topic><topic>Pregnancy</topic><topic>Pregnancy Trimester, Third</topic><topic>Troponin</topic><topic>Troponin I - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Joyal, Dominique, MD</creatorcontrib><creatorcontrib>Leya, Ferdinand, MD</creatorcontrib><creatorcontrib>Koh, Megan, MD</creatorcontrib><creatorcontrib>Besinger, Richard, MD</creatorcontrib><creatorcontrib>Ramana, Ravi, DO</creatorcontrib><creatorcontrib>Kahn, Steven, PhD</creatorcontrib><creatorcontrib>Jeske, Walter, PhD</creatorcontrib><creatorcontrib>Lewis, Bruce, MD</creatorcontrib><creatorcontrib>Steen, Lowell, MD</creatorcontrib><creatorcontrib>Mestril, Ruben, PhD</creatorcontrib><creatorcontrib>Arab, Dinesh, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Joyal, Dominique, MD</au><au>Leya, Ferdinand, MD</au><au>Koh, Megan, MD</au><au>Besinger, Richard, MD</au><au>Ramana, Ravi, DO</au><au>Kahn, Steven, PhD</au><au>Jeske, Walter, PhD</au><au>Lewis, Bruce, MD</au><au>Steen, Lowell, MD</au><au>Mestril, Ruben, PhD</au><au>Arab, Dinesh, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Troponin I Levels in Patients with Preeclampsia</atitle><jtitle>The American journal of medicine</jtitle><addtitle>Am J Med</addtitle><date>2007-09-01</date><risdate>2007</risdate><volume>120</volume><issue>9</issue><spage>819.e13</spage><epage>819.e14</epage><pages>819.e13-819.e14</pages><issn>0002-9343</issn><eissn>1555-7162</eissn><abstract>Abstract Introduction Preeclampsia involves a diffuse inflammatory state and elevated levels of troponins in patients with preeclampsia have been anecdotally reported. It is, however, unknown whether it is attributable to the preeclampsia. Objective We sought to determine the troponin I levels at the time of delivery in pregnant women with and without preeclampsia. Methods Plasma samples were obtained at the time of delivery and serum troponin I was measured by ELISA method. Results Thirty-nine women were included (20 with preeclampsia and 19 without). Mean troponin I level was 0.008 ng/mL in patients with preeclampsia and 0.01 ng/mL in controls ( P =.59). The highest troponin I level was 0.04 ng/mL for both patients with and without preeclampsia. Conclusions Preeclampsia was not associated with a rise in troponin I levels in our study. Patients with preeclampsia and elevated troponin levels should have further cardiac investigations.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>17765054</pmid><doi>10.1016/j.amjmed.2006.05.068</doi></addata></record> |
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| subjects | Adult Endothelium, Vascular - physiopathology Female Humans Internal Medicine Pre-Eclampsia - blood Pre-Eclampsia - physiopathology preeclampsia Pregnancy Pregnancy Trimester, Third Troponin Troponin I - blood |
| title | Troponin I Levels in Patients with Preeclampsia |
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