Outcomes of Pregnancies With Fetal Gastroschisis
To describe pregnancy outcomes with fetal gastroschisis, including the associations of prenatal ultrasound findings with neonatal surgical complications and other morbidities. This was a review of pregnancies complicated by fetal gastroschisis and delivered from January 1998 through June 2006. The l...
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| Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 2007-09, Vol.110 (3), p.663-668 |
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| container_title | Obstetrics and gynecology (New York. 1953) |
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| creator | Santiago-Munoz, Patricia C. McIntire, Donald D. Barber, Robert G. Megison, Stephen M. Twickler, Diane M. Dashe, Jodi S. |
| description | To describe pregnancy outcomes with fetal gastroschisis, including the associations of prenatal ultrasound findings with neonatal surgical complications and other morbidities.
This was a review of pregnancies complicated by fetal gastroschisis and delivered from January 1998 through June 2006. The last ultrasonogram before delivery was reviewed to determine stomach dilatation, bowel dilatation, or abnormalities of amniotic fluid volume. Neonatal records were reviewed to determine type of closure and any bowel complications.
There were 66 pregnancies with gastroschisis, 1 per 2,000 deliveries. There were three stillbirths and three neonatal deaths. Delayed closure was necessary in 49% who underwent surgery. Birth weight below the third percentile, which occurred in 38%, was associated with need for delayed closure, 64% compared with 25% without growth restriction, P |
| doi_str_mv | 10.1097/01.AOG.0000277264.63736.7e |
| format | Article |
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This was a review of pregnancies complicated by fetal gastroschisis and delivered from January 1998 through June 2006. The last ultrasonogram before delivery was reviewed to determine stomach dilatation, bowel dilatation, or abnormalities of amniotic fluid volume. Neonatal records were reviewed to determine type of closure and any bowel complications.
There were 66 pregnancies with gastroschisis, 1 per 2,000 deliveries. There were three stillbirths and three neonatal deaths. Delayed closure was necessary in 49% who underwent surgery. Birth weight below the third percentile, which occurred in 38%, was associated with need for delayed closure, 64% compared with 25% without growth restriction, P<.001, but was not associated with longer hospital stay or neonatal death. Fetal gastroschisis was diagnosed by prenatal ultrasonography in 58 cases. Bowel complications requiring surgery were more frequent when ultrasonography had demonstrated stomach dilatation (five cases), 60% compared with 10%, P=.002. Fetuses with defects so large that no normal ventral wall could be visualized ultrasonographically (three cases) were at increased risk for neonatal death, 100% compared with 0%, P<.001.
Ultrasound findings associated with adverse outcome in fetal gastroschisis included stomach dilatation and a defect so large that no normal ventral wall could be visualized. Fetal growth restriction was common, and such infants were more likely to require delayed gastroschisis closure. Despite more than 90% survival, morbidity with gastroschisis remains high.
II.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>DOI: 10.1097/01.AOG.0000277264.63736.7e</identifier><identifier>PMID: 17766615</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved</publisher><subject>Abdominal Wall - abnormalities ; Abdominal Wall - diagnostic imaging ; Adult ; Biological and medical sciences ; Female ; Fetal Diseases - diagnosis ; Fetal Diseases - diagnostic imaging ; Fetal Diseases - mortality ; Fetal Diseases - surgery ; Fetal Growth Retardation - epidemiology ; Gastric Dilatation - diagnosis ; Gastric Dilatation - diagnostic imaging ; Gastric Dilatation - mortality ; Gastric Dilatation - surgery ; Gastroschisis - diagnosis ; Gastroschisis - diagnostic imaging ; Gastroschisis - mortality ; Gastroschisis - surgery ; Gynecology. Andrology. Obstetrics ; Humans ; Infant Mortality ; Infant, Newborn ; Length of Stay ; Male ; Medical sciences ; Pregnancy ; Pregnancy Outcome ; Risk Assessment ; Stillbirth - epidemiology ; Treatment Outcome ; Ultrasonography, Prenatal - methods</subject><ispartof>Obstetrics and gynecology (New York. 1953), 2007-09, Vol.110 (3), p.663-668</ispartof><rights>by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4440-e454aec959f443a65fd7d7ab62c2f4b92033447130b047a5b63e5f6842cf27613</citedby><cites>FETCH-LOGICAL-c4440-e454aec959f443a65fd7d7ab62c2f4b92033447130b047a5b63e5f6842cf27613</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20283615$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17766615$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Santiago-Munoz, Patricia C.</creatorcontrib><creatorcontrib>McIntire, Donald D.</creatorcontrib><creatorcontrib>Barber, Robert G.</creatorcontrib><creatorcontrib>Megison, Stephen M.</creatorcontrib><creatorcontrib>Twickler, Diane M.</creatorcontrib><creatorcontrib>Dashe, Jodi S.</creatorcontrib><title>Outcomes of Pregnancies With Fetal Gastroschisis</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>To describe pregnancy outcomes with fetal gastroschisis, including the associations of prenatal ultrasound findings with neonatal surgical complications and other morbidities.
This was a review of pregnancies complicated by fetal gastroschisis and delivered from January 1998 through June 2006. The last ultrasonogram before delivery was reviewed to determine stomach dilatation, bowel dilatation, or abnormalities of amniotic fluid volume. Neonatal records were reviewed to determine type of closure and any bowel complications.
There were 66 pregnancies with gastroschisis, 1 per 2,000 deliveries. There were three stillbirths and three neonatal deaths. Delayed closure was necessary in 49% who underwent surgery. Birth weight below the third percentile, which occurred in 38%, was associated with need for delayed closure, 64% compared with 25% without growth restriction, P<.001, but was not associated with longer hospital stay or neonatal death. Fetal gastroschisis was diagnosed by prenatal ultrasonography in 58 cases. Bowel complications requiring surgery were more frequent when ultrasonography had demonstrated stomach dilatation (five cases), 60% compared with 10%, P=.002. Fetuses with defects so large that no normal ventral wall could be visualized ultrasonographically (three cases) were at increased risk for neonatal death, 100% compared with 0%, P<.001.
Ultrasound findings associated with adverse outcome in fetal gastroschisis included stomach dilatation and a defect so large that no normal ventral wall could be visualized. Fetal growth restriction was common, and such infants were more likely to require delayed gastroschisis closure. Despite more than 90% survival, morbidity with gastroschisis remains high.
II.</description><subject>Abdominal Wall - abnormalities</subject><subject>Abdominal Wall - diagnostic imaging</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Fetal Diseases - diagnosis</subject><subject>Fetal Diseases - diagnostic imaging</subject><subject>Fetal Diseases - mortality</subject><subject>Fetal Diseases - surgery</subject><subject>Fetal Growth Retardation - epidemiology</subject><subject>Gastric Dilatation - diagnosis</subject><subject>Gastric Dilatation - diagnostic imaging</subject><subject>Gastric Dilatation - mortality</subject><subject>Gastric Dilatation - surgery</subject><subject>Gastroschisis - diagnosis</subject><subject>Gastroschisis - diagnostic imaging</subject><subject>Gastroschisis - mortality</subject><subject>Gastroschisis - surgery</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant Mortality</subject><subject>Infant, Newborn</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>Risk Assessment</subject><subject>Stillbirth - epidemiology</subject><subject>Treatment Outcome</subject><subject>Ultrasonography, Prenatal - methods</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LAzEQhoMotlb_ghRBb7tOPjbZ9VbEVqFQD4reQjad2NVttya7iP_e9AM7lzDkmZmXh5ArCimFQt0CTUezSQqxmFJMilRyxWWq8Ij0aa54wjh_Pyb9-F8kKheiR85C-Iw8lQU_JT2qlJSSZn0Cs661zRLDsHHDZ48fK7OyVWzfqnYxHGNr6uHEhNY3wS6qUIVzcuJMHfBi_w7I6_jh5f4xmc4mT_ejaWKFEJCgyIRBW2SFE4Ibmbm5mitTSmaZE2XBgHMhFOVQglAmKyXHzMlcMOuYkpQPyM1u79o33x2GVi-rYLGuzQqbLmiZM1aAggje7UAbMwaPTq99tTT-V1PQG18aqI6-9MGX3vrSCuPw5f5KVy5xfhjdC4rA9R4wwZra-Y2e8M8xYDnfcWLH_TR1iz581d0Per1AU7eL7WnJMkgYxMhF7JJNGOB_LTyBpw</recordid><startdate>20070901</startdate><enddate>20070901</enddate><creator>Santiago-Munoz, Patricia C.</creator><creator>McIntire, Donald D.</creator><creator>Barber, Robert G.</creator><creator>Megison, Stephen M.</creator><creator>Twickler, Diane M.</creator><creator>Dashe, Jodi S.</creator><general>by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070901</creationdate><title>Outcomes of Pregnancies With Fetal Gastroschisis</title><author>Santiago-Munoz, Patricia C. ; McIntire, Donald D. ; Barber, Robert G. ; Megison, Stephen M. ; Twickler, Diane M. ; Dashe, Jodi S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4440-e454aec959f443a65fd7d7ab62c2f4b92033447130b047a5b63e5f6842cf27613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Abdominal Wall - abnormalities</topic><topic>Abdominal Wall - diagnostic imaging</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Fetal Diseases - diagnosis</topic><topic>Fetal Diseases - diagnostic imaging</topic><topic>Fetal Diseases - mortality</topic><topic>Fetal Diseases - surgery</topic><topic>Fetal Growth Retardation - epidemiology</topic><topic>Gastric Dilatation - diagnosis</topic><topic>Gastric Dilatation - diagnostic imaging</topic><topic>Gastric Dilatation - mortality</topic><topic>Gastric Dilatation - surgery</topic><topic>Gastroschisis - diagnosis</topic><topic>Gastroschisis - diagnostic imaging</topic><topic>Gastroschisis - mortality</topic><topic>Gastroschisis - surgery</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infant Mortality</topic><topic>Infant, Newborn</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome</topic><topic>Risk Assessment</topic><topic>Stillbirth - epidemiology</topic><topic>Treatment Outcome</topic><topic>Ultrasonography, Prenatal - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Santiago-Munoz, Patricia C.</creatorcontrib><creatorcontrib>McIntire, Donald D.</creatorcontrib><creatorcontrib>Barber, Robert G.</creatorcontrib><creatorcontrib>Megison, Stephen M.</creatorcontrib><creatorcontrib>Twickler, Diane M.</creatorcontrib><creatorcontrib>Dashe, Jodi S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Santiago-Munoz, Patricia C.</au><au>McIntire, Donald D.</au><au>Barber, Robert G.</au><au>Megison, Stephen M.</au><au>Twickler, Diane M.</au><au>Dashe, Jodi S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcomes of Pregnancies With Fetal Gastroschisis</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>2007-09-01</date><risdate>2007</risdate><volume>110</volume><issue>3</issue><spage>663</spage><epage>668</epage><pages>663-668</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>To describe pregnancy outcomes with fetal gastroschisis, including the associations of prenatal ultrasound findings with neonatal surgical complications and other morbidities.
This was a review of pregnancies complicated by fetal gastroschisis and delivered from January 1998 through June 2006. The last ultrasonogram before delivery was reviewed to determine stomach dilatation, bowel dilatation, or abnormalities of amniotic fluid volume. Neonatal records were reviewed to determine type of closure and any bowel complications.
There were 66 pregnancies with gastroschisis, 1 per 2,000 deliveries. There were three stillbirths and three neonatal deaths. Delayed closure was necessary in 49% who underwent surgery. Birth weight below the third percentile, which occurred in 38%, was associated with need for delayed closure, 64% compared with 25% without growth restriction, P<.001, but was not associated with longer hospital stay or neonatal death. Fetal gastroschisis was diagnosed by prenatal ultrasonography in 58 cases. Bowel complications requiring surgery were more frequent when ultrasonography had demonstrated stomach dilatation (five cases), 60% compared with 10%, P=.002. Fetuses with defects so large that no normal ventral wall could be visualized ultrasonographically (three cases) were at increased risk for neonatal death, 100% compared with 0%, P<.001.
Ultrasound findings associated with adverse outcome in fetal gastroschisis included stomach dilatation and a defect so large that no normal ventral wall could be visualized. Fetal growth restriction was common, and such infants were more likely to require delayed gastroschisis closure. Despite more than 90% survival, morbidity with gastroschisis remains high.
II.</abstract><cop>New York, NY</cop><pub>by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved</pub><pmid>17766615</pmid><doi>10.1097/01.AOG.0000277264.63736.7e</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0029-7844 |
| ispartof | Obstetrics and gynecology (New York. 1953), 2007-09, Vol.110 (3), p.663-668 |
| issn | 0029-7844 1873-233X |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Abdominal Wall - abnormalities Abdominal Wall - diagnostic imaging Adult Biological and medical sciences Female Fetal Diseases - diagnosis Fetal Diseases - diagnostic imaging Fetal Diseases - mortality Fetal Diseases - surgery Fetal Growth Retardation - epidemiology Gastric Dilatation - diagnosis Gastric Dilatation - diagnostic imaging Gastric Dilatation - mortality Gastric Dilatation - surgery Gastroschisis - diagnosis Gastroschisis - diagnostic imaging Gastroschisis - mortality Gastroschisis - surgery Gynecology. Andrology. Obstetrics Humans Infant Mortality Infant, Newborn Length of Stay Male Medical sciences Pregnancy Pregnancy Outcome Risk Assessment Stillbirth - epidemiology Treatment Outcome Ultrasonography, Prenatal - methods |
| title | Outcomes of Pregnancies With Fetal Gastroschisis |
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