Severe Acute Respiratory Syndrome Coronavirus ORF6 Antagonizes STAT1 Function by Sequestering Nuclear Import Factors on the Rough Endoplasmic Reticulum/Golgi Membrane

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Veröffentlicht in:	Journal of Virology 2007-09, Vol.81 (18), p.9812-9824
Hauptverfasser:	Frieman, Matthew, Yount, Boyd, Heise, Mark, Kopecky-Bromberg, Sarah A, Palese, Peter, Baric, Ralph S
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus - physiology alpha Karyopherins - genetics alpha Karyopherins - immunology alpha Karyopherins - metabolism Animals beta Karyopherins - genetics beta Karyopherins - immunology beta Karyopherins - metabolism Biological and medical sciences Caco-2 Cells Cell Nucleus - genetics Cell Nucleus - immunology Cell Nucleus - metabolism Cellular Response to Infection Cercopithecus aethiops Endoplasmic Reticulum - genetics Endoplasmic Reticulum - immunology Endoplasmic Reticulum - metabolism Fundamental and applied biological sciences. Psychology Gene Expression Regulation - genetics Gene Expression Regulation - immunology Golgi Apparatus - genetics Golgi Apparatus - immunology Golgi Apparatus - metabolism Humans Immunity, Innate - genetics Interferons - immunology Interferons - metabolism Microbiology Miscellaneous Mutation Open Reading Frames - physiology Protein Structure, Tertiary - genetics Recombinant Proteins - genetics Recombinant Proteins - immunology Recombinant Proteins - metabolism SARS coronavirus SARS Virus - genetics SARS Virus - immunology SARS Virus - metabolism Signal Transduction - genetics Signal Transduction - immunology STAT1 Transcription Factor - genetics STAT1 Transcription Factor - immunology STAT1 Transcription Factor - metabolism Vero Cells Virology Virus Replication - physiology
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