Ageing in yeast does not enhance prion generation

The yeast prions [URE3] and [PSI+] are self‐propagating amyloids of Ure2p and Sup35p, respectively. The analogous transmissible spongiform encephalopathies of mammals and other amyloidoses are largely diseases of later life. From normal strains lacking the prions, we isolated old cells and measured...

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Veröffentlicht in:	Yeast (Chichester, England) England), 2006-12, Vol.23 (16), p.1123-1128
Hauptverfasser:	Shewmaker, Frank, Wickner, Reed B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid - metabolism Glutathione Peroxidase Peptide Termination Factors Prions - metabolism PSI Saccharomyces cerevisiae - chemistry Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Sup35p Time Factors Ure2p URE3
Online-Zugang:	Volltext
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