ATP Stimulates Mouse Embryonic Stem Cell Proliferation via Protein Kinase C, Phosphatidylinositol 3‐Kinase/Akt, and Mitogen‐Activated Protein Kinase Signaling Pathways

This study investigated the effect of ATP and its related signal cascades on the proliferation of mouse ESCs. ATP increased the level of [3H]thymidine/5‐bromo‐2′‐deoxyuridine incorporation and the number of cells in both a time‐ and dose‐dependent manner. AMP‐CPP (a P2X1 and P2X3 agonist), ATP‐γS (a...

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Veröffentlicht in:Stem cells (Dayton, Ohio) Ohio), 2006-12, Vol.24 (12), p.2637-2648
Hauptverfasser: Heo, Jung Sun, Han, Ho Jae
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Sprache:eng
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