Aurora Kinases: New Targets for Cancer Therapy

The Aurora kinase family is a collection of highly related serine/threonine kinases that functions as a key regulator of mitosis. In mammalian cells, Aurora has evolved into three related kinases known as Aurora-A, Aurora-B, and Aurora-C. These kinases are overexpressed in a number of human cancers,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical cancer research 2006-12, Vol.12 (23), p.6869-6875
Hauptverfasser:	CARVAJAL, Richard D, TSE, Archie, SCHWARTZ, Gary K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Aurora kinase A Aurora Kinase B Aurora Kinase C Aurora Kinases Biological and medical sciences Humans Medical sciences Mitotic checkpoint Neoplasms - drug therapy Neoplasms - enzymology Pharmacology. Drug treatments Protein Kinase Inhibitors - pharmacology Protein Kinase Inhibitors - therapeutic use Protein-Serine-Threonine Kinases - antagonists & inhibitors Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!