Apolipoprotein E‐derived antimicrobial peptide analogues with altered membrane affinity and increased potency and breadth of activity

Host‐derived anti‐infective proteins represent an important source of sequences for designing antimicrobial peptides (AMPs). However such sequences are often long and comprise diverse amino acids with uncertain contribution to biological effects. Previously, we identified a simple highly cationic pe...

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Veröffentlicht in:The FEBS journal 2007-09, Vol.274 (17), p.4511-4525
Hauptverfasser: Kelly, Bridie A., Neil, Stuart J., McKnight, Áine, Santos, Joana M., Sinnis, Photini, Jack, Edward R., Middleton, David A., Dobson, Curtis B.
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Sprache:eng
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