Inorganic Polyphosphate: a Possible Stimulant of Bone Formation

Inorganic polyphosphates [Poly(P)] are often distributed in osteoblasts. We undertook the present study to verify the hypothesis that Poly(P) stimulates osteoblasts and facilitates bone formation. The osteoblast-like cell line MC 3T3-E1 was cultured with Poly(P), and gene expression and potential mi...

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Veröffentlicht in:	Journal of dental research 2007-09, Vol.86 (9), p.893-897
Hauptverfasser:	Hacchou, Y., Uematsu, T., Ueda, O., Usui, Y., Uematsu, S., Takahashi, M., Uchihashi, T., Kawazoe, Y., Shiba, T., Kurihara, S., Yamaoka, M., Furusawa, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Alveolar Bone Loss - drug therapy Animals Bone Regeneration - drug effects Cell Differentiation - drug effects Coculture Techniques Collagen Type I - biosynthesis Dentistry Macrophages Male Mice Osteoblasts - drug effects Osteoblasts - metabolism Osteocalcin - biosynthesis Osteoclasts - drug effects Osteogenesis - drug effects Osteopontin - biosynthesis Osteoprotegerin - biosynthesis Phosphates - pharmacology Phosphates - therapeutic use Polyphosphates - pharmacology Polyphosphates - therapeutic use Rats Rats, Wistar
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