Proteome of mesenchymal stem cells
Proteomics has evolved, in recent years, into effective tools for basic and applied stem cell research, and has been extensively used to facilitate the identification of changes in signal transduction components, especially with regard to plasticity, proliferation, and differentiation. Several recen...
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| Veröffentlicht in: | Proteomics (Weinheim) 2007-08, Vol.7 (16), p.2881-2894 |
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| creator | Park, Hye Won Shin, Jun-Seop Kim, Chan-Wha |
| description | Proteomics has evolved, in recent years, into effective tools for basic and applied stem cell research, and has been extensively used to facilitate the identification of changes in signal transduction components, especially with regard to plasticity, proliferation, and differentiation. Several recent reports have also employed proteomic strategies to characterize human mesenchymal stem cells (hMSC) and their differentiated derivatives. Although these approaches have yielded valuable data, the results highlight the fact that only the limited numbers of proteins are characterized at the protein level in these cells, thus necessitating expandable MSC proteome dataset. This review presents, for the first time, an expandable list of MSC proteins, which will function as a starting point for the generation of a comprehensive reference map of their proteome. Also, the better way to bridge current gap between genomics and proteomics study such as integrated proteomic and transcriptomic analyses is discussed. |
| doi_str_mv | 10.1002/pmic.200700089 |
| format | Article |
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Also, the better way to bridge current gap between genomics and proteomics study such as integrated proteomic and transcriptomic analyses is discussed.</description><identifier>ISSN: 1615-9853</identifier><identifier>EISSN: 1615-9861</identifier><identifier>DOI: 10.1002/pmic.200700089</identifier><identifier>PMID: 17654458</identifier><language>eng</language><publisher>Weinheim: Wiley-VCH Verlag</publisher><subject>Analytical, structural and metabolic biochemistry ; Biological and medical sciences ; Fundamental and applied biological sciences. Psychology ; Humans ; Mesenchymal stem cells ; Mesenchymal Stromal Cells - metabolism ; Miscellaneous ; Proteins ; Proteins - genetics ; Proteins - metabolism ; Proteome ; RNA, Messenger - genetics</subject><ispartof>Proteomics (Weinheim), 2007-08, Vol.7 (16), p.2881-2894</ispartof><rights>Copyright © 2007 WILEY‐VCH Verlag GmbH & Co. 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Psychology</subject><subject>Humans</subject><subject>Mesenchymal stem cells</subject><subject>Mesenchymal Stromal Cells - metabolism</subject><subject>Miscellaneous</subject><subject>Proteins</subject><subject>Proteins - genetics</subject><subject>Proteins - metabolism</subject><subject>Proteome</subject><subject>RNA, Messenger - genetics</subject><issn>1615-9853</issn><issn>1615-9861</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMoPqpbl1oE3U29SSavpRStYn2_liGTyejoTKcmLdp_b8qU6k64kEv4zrmHg9Auhh4GIMfjurQ9AiAAQKoVtIk5ZomSHK8ud0Y30FYI7wBYSCXW0QYWnKUpk5vo4NY3E9fUrtsU3doFN7Jvs9pU3TBxdde6qgrbaK0wVXA7i7eDns5OH_vnyfBmcNE_GSaWAVZJTjGBlBpGJFXMMA4qs3mqpMhcLknOCmkVEZZmKs24zJWMnwWXnBY84zSnHXTU-o598zl1YaLrMswTmJFrpkFziZVQBCLYa0HrmxC8K_TYl7XxM41Bz1vR81b0spUo2Fs4T7Pa5b_4ooYIHC4AE6ypCm9Gtgy_nAJCBBeRUy33VVZu9s9ZfXt10f8bImm1Zaz2e6k1_kNHZ8H0y_VADx_o8_X94E5fRn6_5QvTaPPqY56nBwKYRrc4JKU_VAeRzw</recordid><startdate>20070801</startdate><enddate>20070801</enddate><creator>Park, Hye Won</creator><creator>Shin, Jun-Seop</creator><creator>Kim, Chan-Wha</creator><general>Wiley-VCH Verlag</general><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><general>Wiley-VCH</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070801</creationdate><title>Proteome of mesenchymal stem cells</title><author>Park, Hye Won ; Shin, Jun-Seop ; Kim, Chan-Wha</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5019-d312043a528395a5609bcd4987bed82d5f8c927c3b94b68d9882df6863f6b63d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Analytical, structural and metabolic biochemistry</topic><topic>Biological and medical sciences</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Mesenchymal stem cells</topic><topic>Mesenchymal Stromal Cells - metabolism</topic><topic>Miscellaneous</topic><topic>Proteins</topic><topic>Proteins - genetics</topic><topic>Proteins - metabolism</topic><topic>Proteome</topic><topic>RNA, Messenger - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Hye Won</creatorcontrib><creatorcontrib>Shin, Jun-Seop</creatorcontrib><creatorcontrib>Kim, Chan-Wha</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Proteomics (Weinheim)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Hye Won</au><au>Shin, Jun-Seop</au><au>Kim, Chan-Wha</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Proteome of mesenchymal stem cells</atitle><jtitle>Proteomics (Weinheim)</jtitle><addtitle>Proteomics</addtitle><date>2007-08-01</date><risdate>2007</risdate><volume>7</volume><issue>16</issue><spage>2881</spage><epage>2894</epage><pages>2881-2894</pages><issn>1615-9853</issn><eissn>1615-9861</eissn><abstract>Proteomics has evolved, in recent years, into effective tools for basic and applied stem cell research, and has been extensively used to facilitate the identification of changes in signal transduction components, especially with regard to plasticity, proliferation, and differentiation. Several recent reports have also employed proteomic strategies to characterize human mesenchymal stem cells (hMSC) and their differentiated derivatives. Although these approaches have yielded valuable data, the results highlight the fact that only the limited numbers of proteins are characterized at the protein level in these cells, thus necessitating expandable MSC proteome dataset. This review presents, for the first time, an expandable list of MSC proteins, which will function as a starting point for the generation of a comprehensive reference map of their proteome. Also, the better way to bridge current gap between genomics and proteomics study such as integrated proteomic and transcriptomic analyses is discussed.</abstract><cop>Weinheim</cop><pub>Wiley-VCH Verlag</pub><pmid>17654458</pmid><doi>10.1002/pmic.200700089</doi><tpages>14</tpages></addata></record> |
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| ispartof | Proteomics (Weinheim), 2007-08, Vol.7 (16), p.2881-2894 |
| issn | 1615-9853 1615-9861 |
| language | eng |
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| source | MEDLINE; Wiley Journals |
| subjects | Analytical, structural and metabolic biochemistry Biological and medical sciences Fundamental and applied biological sciences. Psychology Humans Mesenchymal stem cells Mesenchymal Stromal Cells - metabolism Miscellaneous Proteins Proteins - genetics Proteins - metabolism Proteome RNA, Messenger - genetics |
| title | Proteome of mesenchymal stem cells |
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