Prismatomerin, a New Iridoid from Prismatomeris tetrandra. Structure Elucidation, Determination of Absolute Configuration, and Cytotoxicity

A new complex iridoid, prismatomerin (1), has been isolated from the leaves of Prismatomeris tetrandra, together with the known glucoside gaertneroside (4). The structures of 1 and 4 were determined by spectroscopic analysis, notably 2D NMR techniques. The (1R,5S,8S,9S,10S)-(−) absolute configuratio...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2007-08, Vol.70 (8), p.1339-1343
Hauptverfasser:	Krohn, Karsten, Gehle, Dietmar, Dey, Sujit Kumar, Nahar, Nilufar, Mosihuzzaman, Mohammed, Sultana, Nasim, Sohrab, Mohammed Hossain, Stephens, Philip J, Pan, Jian-Jung, Sasse, Florenz
Format:	Artikel
Sprache:	eng
Schlagworte:	anticarcinogenic activity Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Bangladesh Biological and medical sciences cell proliferation chemical structure circular dichroism spectroscopy cultured cells cytotoxicity Drug Screening Assays, Antitumor gaertneroside General pharmacology glucosides Humans iridoids Iridoids - chemistry Iridoids - isolation & purification Iridoids - pharmacology isoplumericin Medical sciences medicinal plants mitosis Mitosis - drug effects Molecular Structure Oriental traditional medicine oruwacin Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Leaves - chemistry plumericin plumieride prismatomerin Prismatomeris tetrandra Rubiaceae Rubiaceae - chemistry secondary metabolites spectral analysis
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