Regulatory T cells expressing interleukin 10 develop from Foxp3 + and Foxp3 − precursor cells in the absence of interleukin 10

CD4 + regulatory T cells (T reg cells) that produce interleukin 10 (IL-10) are important contributors to immune homeostasis. We generated mice with a 'dual-reporter' system of the genes encoding IL-10 and the transcription factor Foxp3 to track T reg subsets based on coordinate or differen...

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