Inflammatory syndrome in patients on hemodialysis
Mortality is markedly elevated in hemodialysis (HD) patients. Between 30 and 50% of prevalent patients have elevated serum levels of inflammatory markers such as C-reactive protein and IL-6. The presence of inflammation, chronic or episodic, has been found to be associated with increased mortality r...
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| Veröffentlicht in: | Journal of the American Society of Nephrology 2006-12, Vol.17 (12 Suppl 3), p.S274-S280 |
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| container_end_page | S280 |
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| container_issue | 12 Suppl 3 |
| container_start_page | S274 |
| container_title | Journal of the American Society of Nephrology |
| container_volume | 17 |
| creator | JOFRE, Rosa RODRIGUEZ-BENITEZ, Patrocinio LOPEZ-GOMEZ, Juan M PEREZ-GARCIA, Rafael |
| description | Mortality is markedly elevated in hemodialysis (HD) patients. Between 30 and 50% of prevalent patients have elevated serum levels of inflammatory markers such as C-reactive protein and IL-6. The presence of inflammation, chronic or episodic, has been found to be associated with increased mortality risk. The causes of inflammation are multifactorial and include patient-related factors, such as underlying disease, comorbidity, oxidative stress, infections, obesity, and genetic or immunologic factors, or on the other side, HD-related factors, mainly depending on the membrane biocompatibility and dialysate quality. The adequate knowledge of these causes and their prevention or treatment if possible may contribute to improving the inflammatory state of patients who are on HD and possibly their mortality. |
| doi_str_mv | 10.1681/ASN.2006080926 |
| format | Article |
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Between 30 and 50% of prevalent patients have elevated serum levels of inflammatory markers such as C-reactive protein and IL-6. The presence of inflammation, chronic or episodic, has been found to be associated with increased mortality risk. The causes of inflammation are multifactorial and include patient-related factors, such as underlying disease, comorbidity, oxidative stress, infections, obesity, and genetic or immunologic factors, or on the other side, HD-related factors, mainly depending on the membrane biocompatibility and dialysate quality. The adequate knowledge of these causes and their prevention or treatment if possible may contribute to improving the inflammatory state of patients who are on HD and possibly their mortality.</description><identifier>ISSN: 1046-6673</identifier><identifier>EISSN: 1533-3450</identifier><identifier>DOI: 10.1681/ASN.2006080926</identifier><identifier>PMID: 17130274</identifier><identifier>CODEN: JASNEU</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Emergency and intensive care: renal failure. Dialysis management ; Humans ; Inflammation - etiology ; Inflammation - prevention & control ; Intensive care medicine ; Kidney Failure, Chronic - therapy ; Medical sciences ; Nephrology. 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Between 30 and 50% of prevalent patients have elevated serum levels of inflammatory markers such as C-reactive protein and IL-6. The presence of inflammation, chronic or episodic, has been found to be associated with increased mortality risk. The causes of inflammation are multifactorial and include patient-related factors, such as underlying disease, comorbidity, oxidative stress, infections, obesity, and genetic or immunologic factors, or on the other side, HD-related factors, mainly depending on the membrane biocompatibility and dialysate quality. The adequate knowledge of these causes and their prevention or treatment if possible may contribute to improving the inflammatory state of patients who are on HD and possibly their mortality.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Emergency and intensive care: renal failure. Dialysis management</subject><subject>Humans</subject><subject>Inflammation - etiology</subject><subject>Inflammation - prevention & control</subject><subject>Intensive care medicine</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Medical sciences</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Renal Dialysis - adverse effects</subject><subject>Risk Factors</subject><subject>Syndrome</subject><issn>1046-6673</issn><issn>1533-3450</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkD1PwzAQhi0EoqWwMqIssKXYvvhrrCo-KlUwAHPkxrYwSpxip0P-PUaN1OF0Nzz3Su-D0C3BS8IleVx9vC0pxhxLrCg_Q3PCAEqoGD7PN654ybmAGbpK6QdjwqgQl2hGBAFMRTVHZBNcq7tOD30cizQGE_vOFj4Uez14G4ZU9KH4tl1vvG7H5NM1unC6TfZm2gv09fz0uX4tt-8vm_VqWzbAYSiZw4RYI6ihihFlVcW1dNLuDOeOUSKrPIYIzoABNQCaNtLBTqhcBKiFBXo45u5j_3uwaag7nxrbtjrY_pDq3F4qxVUGl0ewiX1K0bp6H32n41gTXP9LqrOk-iQpP9xNyYddZ80Jn6xk4H4CdGp066IOjU8nTkL2yDH8AZXTbRs</recordid><startdate>20061201</startdate><enddate>20061201</enddate><creator>JOFRE, Rosa</creator><creator>RODRIGUEZ-BENITEZ, Patrocinio</creator><creator>LOPEZ-GOMEZ, Juan M</creator><creator>PEREZ-GARCIA, Rafael</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20061201</creationdate><title>Inflammatory syndrome in patients on hemodialysis</title><author>JOFRE, Rosa ; RODRIGUEZ-BENITEZ, Patrocinio ; LOPEZ-GOMEZ, Juan M ; PEREZ-GARCIA, Rafael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c363t-5f011ed72d29519e946a8f8ebd66f52184218d17653532d33a2c8f3b7909232e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Emergency and intensive care: renal failure. Dialysis management</topic><topic>Humans</topic><topic>Inflammation - etiology</topic><topic>Inflammation - prevention & control</topic><topic>Intensive care medicine</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Medical sciences</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Renal Dialysis - adverse effects</topic><topic>Risk Factors</topic><topic>Syndrome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JOFRE, Rosa</creatorcontrib><creatorcontrib>RODRIGUEZ-BENITEZ, Patrocinio</creatorcontrib><creatorcontrib>LOPEZ-GOMEZ, Juan M</creatorcontrib><creatorcontrib>PEREZ-GARCIA, Rafael</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Society of Nephrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JOFRE, Rosa</au><au>RODRIGUEZ-BENITEZ, Patrocinio</au><au>LOPEZ-GOMEZ, Juan M</au><au>PEREZ-GARCIA, Rafael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inflammatory syndrome in patients on hemodialysis</atitle><jtitle>Journal of the American Society of Nephrology</jtitle><addtitle>J Am Soc Nephrol</addtitle><date>2006-12-01</date><risdate>2006</risdate><volume>17</volume><issue>12 Suppl 3</issue><spage>S274</spage><epage>S280</epage><pages>S274-S280</pages><issn>1046-6673</issn><eissn>1533-3450</eissn><coden>JASNEU</coden><abstract>Mortality is markedly elevated in hemodialysis (HD) patients. Between 30 and 50% of prevalent patients have elevated serum levels of inflammatory markers such as C-reactive protein and IL-6. The presence of inflammation, chronic or episodic, has been found to be associated with increased mortality risk. The causes of inflammation are multifactorial and include patient-related factors, such as underlying disease, comorbidity, oxidative stress, infections, obesity, and genetic or immunologic factors, or on the other side, HD-related factors, mainly depending on the membrane biocompatibility and dialysate quality. The adequate knowledge of these causes and their prevention or treatment if possible may contribute to improving the inflammatory state of patients who are on HD and possibly their mortality.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>17130274</pmid><doi>10.1681/ASN.2006080926</doi><oa>free_for_read</oa></addata></record> |
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| issn | 1046-6673 1533-3450 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Emergency and intensive care: renal failure. Dialysis management Humans Inflammation - etiology Inflammation - prevention & control Intensive care medicine Kidney Failure, Chronic - therapy Medical sciences Nephrology. Urinary tract diseases Renal Dialysis - adverse effects Risk Factors Syndrome |
| title | Inflammatory syndrome in patients on hemodialysis |
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