The contributions of microtubule stability and dynamic instability to adenovirus nuclear localization efficiency

Adenoviruses (Ads) utilize host cell microtubules to traverse the intracellular space and reach the nucleus in a highly efficient manner. Previous studies have shown that Ad infection promotes the formation of stable, posttranslationally modified microtubules by a RhoA‐dependent mechanism. Ad infect...

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Veröffentlicht in:	Cell motility and the cytoskeleton 2007-09, Vol.64 (9), p.675-689
Hauptverfasser:	Warren, James C., Cassimeris, Lynne
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Active Transport, Cell Nucleus Adenoviridae - metabolism Adenoviridae Infections - metabolism Cell Line, Tumor Cell Nucleus - metabolism Cell Nucleus - virology Enzyme Activation Humans microtubule acetylation Microtubules - metabolism Microtubules - virology paclitaxel Protein Processing, Post-Translational Rac1 rac1 GTP-Binding Protein - metabolism RhoA rhoA GTP-Binding Protein - metabolism trichostatin A Virus Internalization
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