Protein scission by metal ion-ascorbate system

About 14 proteins were tested for specific oxidative scission catalyzed by metal ions in the presence of ascorbate and oxidizing agents (O(2) or hydrogen peroxide). Only four of them were degraded by Fe(3+)/Fe(2+)- ascorbate, twelve - by Cu(2+)/Cu(+)-ascorbate and two proteins (alpha- and beta-casei...

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Veröffentlicht in:	The Protein Journal 2006-09, Vol.25 (6), p.369-378
Hauptverfasser:	Sereikaite, Jolanta, Jachno, Jelena, Santockyte, Rasa, Chmielevski, Piotr, Bumelis, Vladas-Algirdas, Dienys, Gervydas
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Ascorbic Acid - chemistry Binding Sites Carbonyl compounds Cations - chemistry Electrophoresis, Polyacrylamide Gel Human Growth Hormone - chemistry Human Growth Hormone - metabolism Humans Hydrogen peroxide Hydrogen-Ion Concentration Metal ions Molecular Structure Oxidizing agents Protein Binding Proteins Proteins - chemistry Proteins - metabolism Temperature
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