Anticancer medicines in development: assessment of bioactivity profiles within the National Cancer Institute anticancer screening data

We present an analysis of current anticancer compounds that are in phase I, II, or III clinical trials and their structural analogues that have been screened in the National Cancer Institute (NCI) anticancer screening program. Bioactivity profiles, measured across the NCI 60 cell lines, were examine...

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Veröffentlicht in:	Molecular cancer therapeutics 2007-08, Vol.6 (8), p.2261-2270
Hauptverfasser:	Covell, David G, Huang, Ruili, Wallqvist, Anders
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer Medicines Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Bioactivity Profiles Cell Line, Tumor Drug Discovery Drug Screening Assays, Antitumor Humans National Institutes of Health (U.S.) NCI-60 ROC Curve United States
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