Glutamate and schizophrenia: beyond the dopamine hypothesis

: 1. After 50 years of antipsychotic drug development focused on the dopamine D2 receptor, schizophrenia remains a chronic, disabling disorder for most affected individuals. 2. Studies over the last decade demonstrate that administration of low doses of NMDA receptor antagonists can cause in normal...

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Veröffentlicht in:	Cellular and molecular neurobiology 2006-07, Vol.26 (4-6), p.365-382
1. Verfasser:	Coyle, Joseph T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipsychotic Agents - therapeutic use Dopamine - physiology Glutamates - physiology Humans Models, Biological Receptors, N-Methyl-D-Aspartate - physiology Schizophrenia - drug therapy Schizophrenia - etiology Synaptic Transmission
Online-Zugang:	Volltext
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