Effects of oral preload, CCK or bombesin administration on short term food intake of melanocortin 4-receptor knockout (MC4RKO) mice

We investigated whether either heterozygous (HET) or homozygous (knockout, KO) disruption of the melanocortin type 4 receptor (MC4R) gene alters post ingestive responsiveness of mice. Specifically, we tested the hypothesis that hyperphagia in MC4RKO mice might be due to a deficit in processes that s...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2006-12, Vol.27 (12), p.3226-3233
Hauptverfasser:	Vaughan, C.H., Haskell-Luevano, C., Andreasen, A., Rowland, N.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bombesin Bombesin - administration & dosage Bombesin - physiology Cholecystokinin Cholecystokinin - administration & dosage Cholecystokinin - physiology Eating - genetics Fundamental and applied biological sciences. Psychology Gut Hyperphagia - genetics MC4RKO mice Mice Mice, Knockout Preload Receptor, Melanocortin, Type 4 - deficiency Receptor, Melanocortin, Type 4 - genetics Satiety Satiety Response - physiology Vertebrates: endocrinology
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