Retrograde BMP Signaling Regulates Trigeminal Sensory Neuron Identities and the Formation of Precise Face Maps

Somatosensory information from the face is transmitted to the brain by trigeminal sensory neurons. It was previously unknown whether neurons innervating distinct areas of the face possess molecular differences. We have identified a set of genes differentially expressed along the dorsoventral axis of...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2007-08, Vol.55 (4), p.572-586
Hauptverfasser:	Hodge, Liberty K., Klassen, Matthew P., Han, Bao-Xia, Yiu, Glenn, Hurrell, Joanna, Howell, Audrey, Rousseau, Guy, Lemaigre, Frederic, Tessier-Lavigne, Marc, Wang, Fan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Patterning - genetics Body Patterning - physiology Bone Morphogenetic Protein 4 Bone Morphogenetic Proteins - genetics Bone Morphogenetic Proteins - metabolism Brain Mapping Cells, Cultured DEVBIO Embryo, Mammalian Experiments Face - embryology Gene expression Gene Expression Regulation, Developmental Homeodomain Proteins - metabolism In Situ Hybridization Mice Mice, Transgenic MOLNEURO Nerve Tissue Proteins - metabolism Neurons Neurons, Afferent - physiology Signal Transduction - genetics Signal Transduction - physiology Skin Transcription factors Transcription Factors - metabolism Trigeminal Ganglion - cytology Trigeminal Ganglion - embryology Wnt1 Protein - genetics
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