Proteinuria-Lowering Effect of Heparin Therapy in Diabetic Nephropathy without Affecting the Renin-Angiotensin-Aldosterone System

Angiotensin-converting enzyme inhibitors and angiotensin II (AngII) type 1 receptor blockers lower proteinuria and preserve renal function in diabetic nephropathy (DN). The antiproteinuric effects are greater than their blood pressure reduction, involving the sieving properties of the glomerular fil...

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Veröffentlicht in:	Clinical journal of the American Society of Nephrology 2007-01, Vol.2 (1), p.58-67
Hauptverfasser:	Benck, Urs, Haeckel, Sarah, Clorius, John H, van der Woude, Fokko J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aldosterone - blood Blood Pressure - drug effects Diabetic Nephropathies - complications Diabetic Nephropathies - diagnostic imaging Diabetic Nephropathies - drug therapy Enoxaparin - administration & dosage Female Fibrinolytic Agents - administration & dosage Glomerular Filtration Rate - drug effects Hippurates - pharmacokinetics Humans Iodine Radioisotopes Male Middle Aged Models, Biological Prospective Studies Proteinuria - diagnostic imaging Proteinuria - drug therapy Proteinuria - etiology Radionuclide Imaging Renal Circulation - drug effects Renin-Angiotensin System - physiology Technetium Tc 99m Pentetate Treatment Outcome
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