General Nature of the STAT3-Activated Anti-Inflammatory Response

Although many cytokine receptors generate their signals via the STAT3 pathway, the IL-10R appears unique in promoting a potent anti-inflammatory response (AIR) via STAT3 to antagonize proinflammatory signals that activate the innate immune response. We found that heterologous cytokine receptor syste...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of Immunology 2006-12, Vol.177 (11), p.7880-7888
Hauptverfasser:	El Kasmi, Karim C, Holst, Jeff, Coffre, Maryaline, Mielke, Lisa, de Pauw, Antoine, Lhocine, Nouara, Smith, Amber M, Rutschman, Robert, Kaushal, Deepak, Shen, Yuhong, Suda, Takashi, Donnelly, Raymond P, Myers, Martin G., Jr, Alexander, Warren, Vignali, Dario A. A, Watowich, Stephanie S, Ernst, Matthias, Hilton, Douglas J, Murray, Peter J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Enzyme-Linked Immunosorbent Assay Gene Expression Immunoblotting Inflammation Interleukin-10 - metabolism Interleukin-6 - metabolism Mice Oligonucleotide Array Sequence Analysis Receptors, Interleukin-10 - metabolism Reverse Transcriptase Polymerase Chain Reaction Signal Transduction - immunology STAT3 Transcription Factor - metabolism Suppressor of Cytokine Signaling 3 Protein Suppressor of Cytokine Signaling Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!