Measurement of Rifampicin and Clarithromycin in Serum by High-performance Liquid Chromatography with Electrochemical Detection

Rifampicin (RFP) induces hepatic drug-metabolizing enzymes, making drug interactions a very important clinical problem. Clarithromycin (CAM) metabolism is reportedly enhanced by induction of hepatic drug-metabolizing enzymes (CYP3A4) by RFP, so that the blood lend of CAM decreases when RFP is admini...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Kansenshogaku Zasshi 2007/07/20, Vol.81(4), pp.414-420
Hauptverfasser:	TAKI, Hisashi, OGAWA, Kenji, NAKAGAWA, Taku, NIKAI, Toshiaki
Format:	Artikel
Sprache:	jpn
Schlagworte:	Aged Chromatography, High Pressure Liquid clarithromycin Clarithromycin - blood electrochemical detector Electrochemistry Female high-performance liquid chromatography Humans Liver - metabolism rifampicin Rifampin - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!