Potentially inappropriate medication prescribing for elderly outpatients in emilia romagna, Italy : A population-based cohort study
In the US, a growing body of epidemiological studies has documented widespread potentially inappropriate medication prescribing among the elderly in outpatient settings. However, only limited information exists in Europe. To evaluate the prevalence of potentially inappropriate medication prescribing...
Gespeichert in:
| Veröffentlicht in: | Drugs & aging 2006-01, Vol.23 (11), p.915-924 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 924 |
|---|---|
| container_issue | 11 |
| container_start_page | 915 |
| container_title | Drugs & aging |
| container_volume | 23 |
| creator | MAIO, Vittorio YUEN, Elaine J NOVIELLI, Karen SMITH, Kenneth D LOUIS, Daniel Z |
| description | In the US, a growing body of epidemiological studies has documented widespread potentially inappropriate medication prescribing among the elderly in outpatient settings. However, only limited information exists in Europe.
To evaluate the prevalence of potentially inappropriate medication prescribing among elderly outpatients in Emilia Romagna, Italy and to investigate factors associated with potentially inappropriate medication prescribing in that setting.
Retrospective cohort study using the Emilia Romagna outpatient prescription claims database from 1 January 2001 to 31 December 2001 linked with information (age, sex and other variables) available from a demographic file of approximately 1 million Emilia Romagna residents aged >or=65 years. The cohort comprised 849 425 elderly patients who had at least one drug prescription during the study period. The prevalence of potentially inappropriate medication prescribing, as defined by the 2002 Beers' criteria, was measured together with predictors associated with potentially inappropriate medication prescribing.
A total of 152 641 (18%) elderly Emilia Romagna outpatients had one or more occurrences of potentially inappropriate medication prescribing. Of these, 11.5% received prescriptions for two medications of concern and 1.7% for three or more. Doxazosin (prescribed to 23% of subjects) was the most frequently occurring potentially inappropriate prescribed medication, followed by ketorolac (20.5%), ticlopidine (18.3%) and amiodarone (12.6%). Factors associated with greater likelihood of potentially inappropriate medication prescribing were older age, overall number of drugs prescribed and greater number of chronic conditions. The odds of receiving potentially inappropriate prescribed medications were lower for females, subjects living in more urban areas and subjects with a higher income level.
This study provides strong evidence that potentially inappropriate medication prescribing for elderly outpatients is a substantial problem in Emilia Romagna. Focusing on the prevalence of potentially inappropriate medication prescribing and associated predictors can help in the development of educational programmes targeting outpatient practitioners to influence prescribing behaviour and, therefore, reduce potentially inappropriate medication prescribing. |
| doi_str_mv | 10.2165/00002512-200623110-00006 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_68157330</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A200671297</galeid><sourcerecordid>A200671297</sourcerecordid><originalsourceid>FETCH-LOGICAL-c355t-30db8afb32add0ef14aa8a57cc916724919a870d03facb5155d07779b167aca13</originalsourceid><addsrcrecordid>eNptkU9v1DAQxSMEon_gKyBLCE5N63HqOOa2qlqoVIkeQOJmTWxnMXLiYDuHPfPFcXYXKiTsg0fj3xvZ71UVAXrJoOVXtCzGgdWM0pY1ALReW-2z6hRAyBpkK5_va1ozJr-dVGcp_VgJxuBldQICqOStPK1-PYZsp-zQ-x1xE85zDHN0mC0ZrXEaswsTmaNNOrreTVsyhEisNzYWQVjyXIgyIBUxsaPzDkkMI24nvCD3GQv0gWzIHObF72fVPSZriA7fQ8wk5cXsXlUvBvTJvj6e59XXu9svN5_qh88f7282D7VuOM91Q03f4dA3DI2hdoBrxA650FpCK9i1BImdoIY2A-qeA-eGCiFkX25RIzTn1fvD3PLHn4tNWY0uaes9TjYsSbUdcNE0tIBvD-AWvVVuGkKOqFdYbVbHBTApCnX5H6psU3zQYbKDK_1_BN1BoGNIKdpBFadHjDsFVK25qj-5qr-57lttkb45Pn3pSy5PwmOQBXh3BDBp9EPESbv0xHXFwlay5jeJ5awH</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68157330</pqid></control><display><type>article</type><title>Potentially inappropriate medication prescribing for elderly outpatients in emilia romagna, Italy : A population-based cohort study</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>MAIO, Vittorio ; YUEN, Elaine J ; NOVIELLI, Karen ; SMITH, Kenneth D ; LOUIS, Daniel Z</creator><creatorcontrib>MAIO, Vittorio ; YUEN, Elaine J ; NOVIELLI, Karen ; SMITH, Kenneth D ; LOUIS, Daniel Z</creatorcontrib><description>In the US, a growing body of epidemiological studies has documented widespread potentially inappropriate medication prescribing among the elderly in outpatient settings. However, only limited information exists in Europe.
To evaluate the prevalence of potentially inappropriate medication prescribing among elderly outpatients in Emilia Romagna, Italy and to investigate factors associated with potentially inappropriate medication prescribing in that setting.
Retrospective cohort study using the Emilia Romagna outpatient prescription claims database from 1 January 2001 to 31 December 2001 linked with information (age, sex and other variables) available from a demographic file of approximately 1 million Emilia Romagna residents aged >or=65 years. The cohort comprised 849 425 elderly patients who had at least one drug prescription during the study period. The prevalence of potentially inappropriate medication prescribing, as defined by the 2002 Beers' criteria, was measured together with predictors associated with potentially inappropriate medication prescribing.
A total of 152 641 (18%) elderly Emilia Romagna outpatients had one or more occurrences of potentially inappropriate medication prescribing. Of these, 11.5% received prescriptions for two medications of concern and 1.7% for three or more. Doxazosin (prescribed to 23% of subjects) was the most frequently occurring potentially inappropriate prescribed medication, followed by ketorolac (20.5%), ticlopidine (18.3%) and amiodarone (12.6%). Factors associated with greater likelihood of potentially inappropriate medication prescribing were older age, overall number of drugs prescribed and greater number of chronic conditions. The odds of receiving potentially inappropriate prescribed medications were lower for females, subjects living in more urban areas and subjects with a higher income level.
This study provides strong evidence that potentially inappropriate medication prescribing for elderly outpatients is a substantial problem in Emilia Romagna. Focusing on the prevalence of potentially inappropriate medication prescribing and associated predictors can help in the development of educational programmes targeting outpatient practitioners to influence prescribing behaviour and, therefore, reduce potentially inappropriate medication prescribing.</description><identifier>ISSN: 1170-229X</identifier><identifier>EISSN: 1179-1969</identifier><identifier>DOI: 10.2165/00002512-200623110-00006</identifier><identifier>PMID: 17109569</identifier><language>eng</language><publisher>Auckland: Adis International</publisher><subject>Aged ; Aged, 80 and over ; Antihypertensive Agents - therapeutic use ; Biological and medical sciences ; Cohort Studies ; Doxazosin - therapeutic use ; Drug Prescriptions ; Female ; General pharmacology ; Humans ; Italy ; Male ; Medical sciences ; Medication Errors - statistics & numerical data ; Miscellaneous ; Outpatients - statistics & numerical data ; Pharmacology. Drug treatments ; Professional Practice - standards</subject><ispartof>Drugs & aging, 2006-01, Vol.23 (11), p.915-924</ispartof><rights>2007 INIST-CNRS</rights><rights>COPYRIGHT 2006 Wolters Kluwer Health, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c355t-30db8afb32add0ef14aa8a57cc916724919a870d03facb5155d07779b167aca13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18355692$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17109569$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MAIO, Vittorio</creatorcontrib><creatorcontrib>YUEN, Elaine J</creatorcontrib><creatorcontrib>NOVIELLI, Karen</creatorcontrib><creatorcontrib>SMITH, Kenneth D</creatorcontrib><creatorcontrib>LOUIS, Daniel Z</creatorcontrib><title>Potentially inappropriate medication prescribing for elderly outpatients in emilia romagna, Italy : A population-based cohort study</title><title>Drugs & aging</title><addtitle>Drugs Aging</addtitle><description>In the US, a growing body of epidemiological studies has documented widespread potentially inappropriate medication prescribing among the elderly in outpatient settings. However, only limited information exists in Europe.
To evaluate the prevalence of potentially inappropriate medication prescribing among elderly outpatients in Emilia Romagna, Italy and to investigate factors associated with potentially inappropriate medication prescribing in that setting.
Retrospective cohort study using the Emilia Romagna outpatient prescription claims database from 1 January 2001 to 31 December 2001 linked with information (age, sex and other variables) available from a demographic file of approximately 1 million Emilia Romagna residents aged >or=65 years. The cohort comprised 849 425 elderly patients who had at least one drug prescription during the study period. The prevalence of potentially inappropriate medication prescribing, as defined by the 2002 Beers' criteria, was measured together with predictors associated with potentially inappropriate medication prescribing.
A total of 152 641 (18%) elderly Emilia Romagna outpatients had one or more occurrences of potentially inappropriate medication prescribing. Of these, 11.5% received prescriptions for two medications of concern and 1.7% for three or more. Doxazosin (prescribed to 23% of subjects) was the most frequently occurring potentially inappropriate prescribed medication, followed by ketorolac (20.5%), ticlopidine (18.3%) and amiodarone (12.6%). Factors associated with greater likelihood of potentially inappropriate medication prescribing were older age, overall number of drugs prescribed and greater number of chronic conditions. The odds of receiving potentially inappropriate prescribed medications were lower for females, subjects living in more urban areas and subjects with a higher income level.
This study provides strong evidence that potentially inappropriate medication prescribing for elderly outpatients is a substantial problem in Emilia Romagna. Focusing on the prevalence of potentially inappropriate medication prescribing and associated predictors can help in the development of educational programmes targeting outpatient practitioners to influence prescribing behaviour and, therefore, reduce potentially inappropriate medication prescribing.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antihypertensive Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cohort Studies</subject><subject>Doxazosin - therapeutic use</subject><subject>Drug Prescriptions</subject><subject>Female</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>Italy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medication Errors - statistics & numerical data</subject><subject>Miscellaneous</subject><subject>Outpatients - statistics & numerical data</subject><subject>Pharmacology. Drug treatments</subject><subject>Professional Practice - standards</subject><issn>1170-229X</issn><issn>1179-1969</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkU9v1DAQxSMEon_gKyBLCE5N63HqOOa2qlqoVIkeQOJmTWxnMXLiYDuHPfPFcXYXKiTsg0fj3xvZ71UVAXrJoOVXtCzGgdWM0pY1ALReW-2z6hRAyBpkK5_va1ozJr-dVGcp_VgJxuBldQICqOStPK1-PYZsp-zQ-x1xE85zDHN0mC0ZrXEaswsTmaNNOrreTVsyhEisNzYWQVjyXIgyIBUxsaPzDkkMI24nvCD3GQv0gWzIHObF72fVPSZriA7fQ8wk5cXsXlUvBvTJvj6e59XXu9svN5_qh88f7282D7VuOM91Q03f4dA3DI2hdoBrxA650FpCK9i1BImdoIY2A-qeA-eGCiFkX25RIzTn1fvD3PLHn4tNWY0uaes9TjYsSbUdcNE0tIBvD-AWvVVuGkKOqFdYbVbHBTApCnX5H6psU3zQYbKDK_1_BN1BoGNIKdpBFadHjDsFVK25qj-5qr-57lttkb45Pn3pSy5PwmOQBXh3BDBp9EPESbv0xHXFwlay5jeJ5awH</recordid><startdate>20060101</startdate><enddate>20060101</enddate><creator>MAIO, Vittorio</creator><creator>YUEN, Elaine J</creator><creator>NOVIELLI, Karen</creator><creator>SMITH, Kenneth D</creator><creator>LOUIS, Daniel Z</creator><general>Adis International</general><general>Wolters Kluwer Health, Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060101</creationdate><title>Potentially inappropriate medication prescribing for elderly outpatients in emilia romagna, Italy : A population-based cohort study</title><author>MAIO, Vittorio ; YUEN, Elaine J ; NOVIELLI, Karen ; SMITH, Kenneth D ; LOUIS, Daniel Z</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c355t-30db8afb32add0ef14aa8a57cc916724919a870d03facb5155d07779b167aca13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antihypertensive Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Cohort Studies</topic><topic>Doxazosin - therapeutic use</topic><topic>Drug Prescriptions</topic><topic>Female</topic><topic>General pharmacology</topic><topic>Humans</topic><topic>Italy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medication Errors - statistics & numerical data</topic><topic>Miscellaneous</topic><topic>Outpatients - statistics & numerical data</topic><topic>Pharmacology. Drug treatments</topic><topic>Professional Practice - standards</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MAIO, Vittorio</creatorcontrib><creatorcontrib>YUEN, Elaine J</creatorcontrib><creatorcontrib>NOVIELLI, Karen</creatorcontrib><creatorcontrib>SMITH, Kenneth D</creatorcontrib><creatorcontrib>LOUIS, Daniel Z</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Drugs & aging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MAIO, Vittorio</au><au>YUEN, Elaine J</au><au>NOVIELLI, Karen</au><au>SMITH, Kenneth D</au><au>LOUIS, Daniel Z</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potentially inappropriate medication prescribing for elderly outpatients in emilia romagna, Italy : A population-based cohort study</atitle><jtitle>Drugs & aging</jtitle><addtitle>Drugs Aging</addtitle><date>2006-01-01</date><risdate>2006</risdate><volume>23</volume><issue>11</issue><spage>915</spage><epage>924</epage><pages>915-924</pages><issn>1170-229X</issn><eissn>1179-1969</eissn><abstract>In the US, a growing body of epidemiological studies has documented widespread potentially inappropriate medication prescribing among the elderly in outpatient settings. However, only limited information exists in Europe.
To evaluate the prevalence of potentially inappropriate medication prescribing among elderly outpatients in Emilia Romagna, Italy and to investigate factors associated with potentially inappropriate medication prescribing in that setting.
Retrospective cohort study using the Emilia Romagna outpatient prescription claims database from 1 January 2001 to 31 December 2001 linked with information (age, sex and other variables) available from a demographic file of approximately 1 million Emilia Romagna residents aged >or=65 years. The cohort comprised 849 425 elderly patients who had at least one drug prescription during the study period. The prevalence of potentially inappropriate medication prescribing, as defined by the 2002 Beers' criteria, was measured together with predictors associated with potentially inappropriate medication prescribing.
A total of 152 641 (18%) elderly Emilia Romagna outpatients had one or more occurrences of potentially inappropriate medication prescribing. Of these, 11.5% received prescriptions for two medications of concern and 1.7% for three or more. Doxazosin (prescribed to 23% of subjects) was the most frequently occurring potentially inappropriate prescribed medication, followed by ketorolac (20.5%), ticlopidine (18.3%) and amiodarone (12.6%). Factors associated with greater likelihood of potentially inappropriate medication prescribing were older age, overall number of drugs prescribed and greater number of chronic conditions. The odds of receiving potentially inappropriate prescribed medications were lower for females, subjects living in more urban areas and subjects with a higher income level.
This study provides strong evidence that potentially inappropriate medication prescribing for elderly outpatients is a substantial problem in Emilia Romagna. Focusing on the prevalence of potentially inappropriate medication prescribing and associated predictors can help in the development of educational programmes targeting outpatient practitioners to influence prescribing behaviour and, therefore, reduce potentially inappropriate medication prescribing.</abstract><cop>Auckland</cop><pub>Adis International</pub><pmid>17109569</pmid><doi>10.2165/00002512-200623110-00006</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1170-229X |
| ispartof | Drugs & aging, 2006-01, Vol.23 (11), p.915-924 |
| issn | 1170-229X 1179-1969 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68157330 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Aged Aged, 80 and over Antihypertensive Agents - therapeutic use Biological and medical sciences Cohort Studies Doxazosin - therapeutic use Drug Prescriptions Female General pharmacology Humans Italy Male Medical sciences Medication Errors - statistics & numerical data Miscellaneous Outpatients - statistics & numerical data Pharmacology. Drug treatments Professional Practice - standards |
| title | Potentially inappropriate medication prescribing for elderly outpatients in emilia romagna, Italy : A population-based cohort study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T00%3A26%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Potentially%20inappropriate%20medication%20prescribing%20for%20elderly%20outpatients%20in%20emilia%20romagna,%20Italy%20:%20A%20population-based%20cohort%20study&rft.jtitle=Drugs%20&%20aging&rft.au=MAIO,%20Vittorio&rft.date=2006-01-01&rft.volume=23&rft.issue=11&rft.spage=915&rft.epage=924&rft.pages=915-924&rft.issn=1170-229X&rft.eissn=1179-1969&rft_id=info:doi/10.2165/00002512-200623110-00006&rft_dat=%3Cgale_proqu%3EA200671297%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68157330&rft_id=info:pmid/17109569&rft_galeid=A200671297&rfr_iscdi=true |