[D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse)

Two melanocortin receptors (MC1 and MC3R) have been identified as main transducers of the anti-inflammatory effects of natural and synthetic melanocortins. In this study, we have taken advantage of the recent description of the selective MC3R agonist [d-Trp(8)]-gamma-melanocyte-stimulating hormone (...

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Veröffentlicht in:Molecular pharmacology 2006-12, Vol.70 (6), p.1850-1855
Hauptverfasser: Getting, Stephen J, Lam, Connie W, Leoni, Giovanna, Gavins, Felicity N E, Grieco, Paolo, Perretti, Mauro
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Sprache:eng
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