Increased frequencies of glutathione- S -transferase (GSTM1 and GSTT1) null genotypes in Indian patients with chronic myeloid leukemia

Abstract Inherited differences in the capacity of xenobiotic metabolizing enzymes might be an important factor in genetic susceptibility to cancer. Null genotypes of glutathione- S -transferases (GSTs) exhibit absence of enzymatic activity and are hypothesized to be at increased risk of developing c...

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Veröffentlicht in:	Leukemia research 2007-10, Vol.31 (10), p.1359-1363
Hauptverfasser:	Bajpai, Prachi, Tripathi, Anil Kumar, Agrawal, Deepa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Case-Control Studies CML Female Genetic Predisposition to Disease Genotype Glutathione Transferase - genetics Glutathione- S-transferase Hematology, Oncology and Palliative Medicine Humans India Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Male Polymerase Chain Reaction Polymorphism Risk Factors
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