Group sequential t -test for clinical trials with small sample sizes across stages

Abstract Interim analyses are often applied in clinical trials for various reasons. To assess the effect of a clinical treatment, the group sequential t -test with a fixed number of interim analyses is frequently used in clinical trials. The existing critical values used in group sequential t -tests...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Contemporary clinical trials 2007-09, Vol.28 (5), p.563-571
Hauptverfasser:	Shao, Jun, Feng, Huaibao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cardiovascular Clinical trial. Drug monitoring Clinical Trials as Topic - methods Clinical Trials as Topic - statistics & numerical data Data Interpretation, Statistical General pharmacology Hematology, Oncology and Palliative Medicine Humans Interim analysis Medical sciences Monte Carlo Method Pharmacology. Drug treatments Research Design - statistics & numerical data Sample Size Simulation t-statistic Type I error rate
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!