The relationship between white matter brain metabolites and cognition in normal aging: The GENIE study

Abstract Magnetic resonance spectroscopy (MRS) has demonstrated age-related changes in brain metabolites that may underlie micro-structural brain changes, but few studies have examined their relationship with cognitive decline. We performed a cross-sectional study of brain metabolism and cognitive f...

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Veröffentlicht in:	Brain research 2007-08, Vol.1164, p.108-116
Hauptverfasser:	Charlton, R.A, McIntyre, D.J.O, Howe, F.A, Morris, R.G, Markus, H.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Aging Aging - physiology Aspartic Acid - analogs & derivatives Aspartic Acid - analysis Aspartic Acid - metabolism Biological and medical sciences Brain Brain - anatomy & histology Brain - metabolism Cognition Cognition - physiology Cognition Disorders - etiology Cognition Disorders - metabolism Cognition Disorders - physiopathology Cross-Sectional Studies Development. Senescence. Regeneration. Transplantation Female Fundamental and applied biological sciences. Psychology Humans Intelligence - physiology Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Male Memory Disorders - metabolism Memory Disorders - physiopathology Middle Aged Nerve Fibers, Myelinated - metabolism Neurology Neuropsychological Tests Predictive Value of Tests Vertebrates: nervous system and sense organs Wallerian Degeneration - diagnosis Wallerian Degeneration - metabolism Wallerian Degeneration - physiopathology
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