The receptors and cells for mammalian taste

The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to what was generally believed, it is now clear that distinct cell types expressing unique receptors are tuned to detect each of the five basic tastes: sweet, sour, bitter, salty and umami. Importantly, rece...

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Veröffentlicht in:Nature 2006-11, Vol.444 (7117), p.288-294
Hauptverfasser: Chandrashekar, Jayaram, Hoon, Mark A, Zuker, Charles S, Ryba, Nicholas J. P
Format: Artikel
Sprache:eng
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Zusammenfassung:The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to what was generally believed, it is now clear that distinct cell types expressing unique receptors are tuned to detect each of the five basic tastes: sweet, sour, bitter, salty and umami. Importantly, receptor cells for each taste quality function as dedicated sensors wired to elicit stereotypic responses.
ISSN:0028-0836
1476-4687
1476-4679
DOI:10.1038/nature05401