Baseline HIV Type 1 Coreceptor Tropism Predicts Disease Progression

Background. Human immunodeficiency virus type 1 (HIV-1) coreceptor tropism, the ability of the virus to enter cells via CCR5 or CXCR4, is a viral characteristic mediated by the envelope gene. The impact of coreceptor tropism on the natural history of HIV-1 infection has not been fully explored. Meth...

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Veröffentlicht in:	Clinical infectious diseases 2007-09, Vol.45 (5), p.643-649
Hauptverfasser:	Daar, Eric S., Kesler, Karen L., Petropoulos, Christos J., Huang, Wei, Bates, Michael, Lail, Alice E., Coakley, Eoin P., Gomperts, Edward D., Donfield, Sharyne M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult AIDS Biological and medical sciences Blood plasma CD4 Lymphocyte Count Cell cycle Child Disease Progression Hemophilia Hemophilia A - virology HIV HIV 1 HIV Infections - physiopathology HIV-1 - pathogenicity HIV/AIDS Human immunodeficiency virus Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infections Infectious diseases Kaplan-Meier Estimate Longitudinal Studies Male Medical sciences Phenotypes Receptors, CCR5 - immunology Receptors, CXCR4 - immunology RNA RNA, Viral - blood T cell receptors T lymphocytes Tropisms United States Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load Viruses
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