Polymorphisms in Apoptosis and Cell Cycle Control Genes and Risk of Brain Tumors in Adults

Despite the potential importance of the cell cycle and apoptosis pathways in brain tumor etiology, little has been published regarding brain tumor risk associated with common gene variants in these pathways. Using data from a hospital-based case-control study conducted by the National Cancer Institu...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2007-08, Vol.16 (8), p.1655-1661
Hauptverfasser:	RAJARAMAN, Preetha, WANG, Sophia S, INSKIP, Peter D, ROTHMAN, Nathaniel, BROWN, Merideth M, BLACK, Peter M, FINE, Howard A, LOEFFLER, Jay S, SELKER, Robert G, SHAPIRO, William R, CHANOCK, Stephen J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over apoptosis Apoptosis - genetics Biological and medical sciences brain Brain Neoplasms - genetics case-control Case-Control Studies Caspase 8 - genetics cell cycle Checkpoint Kinase 1 Checkpoint Kinase 2 Cyclin D Cyclin H Cyclin-Dependent Kinase Inhibitor p21 - genetics Cyclins - genetics Exons - genetics Female Genes, cdc Genes, p16 Genes, p53 - genetics Genes, Tumor Suppressor Genetic Variation - genetics glioma Glioma - genetics Haplotypes Humans Male Medical sciences meningioma Meningioma - genetics Middle Aged neoplasm Neurology Neuroma, Acoustic - genetics Polymorphism Polymorphism, Single Nucleotide - genetics Protein Kinases - genetics Protein-Serine-Threonine Kinases - genetics Proto-Oncogene Proteins c-mdm2 - genetics PTEN Phosphohydrolase - genetics Risk Factors tumor Tumors Tumors of the nervous system. Phacomatoses
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