The role of antibiotic and probiotic therapies in current and future management of inflammatory bowel disease
Abundant evidence indicates that the intestinal microflora have a role in the pathogenesis of inflammatory bowel disease (IBD). The composition of the gut microflora is altered in IBD patients with increased "pathogenic" bacteria and decreased bifidobacteria and lactobacilli. In light of t...
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| Veröffentlicht in: | Current gastroenterology reports 2006-12, Vol.8 (6), p.486-498 |
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| creator | Ewaschuk, Julia B Tejpar, Qassim Z Soo, Isaac Madsen, Karen Fedorak, Richard N |
| description | Abundant evidence indicates that the intestinal microflora have a role in the pathogenesis of inflammatory bowel disease (IBD). The composition of the gut microflora is altered in IBD patients with increased "pathogenic" bacteria and decreased bifidobacteria and lactobacilli. In light of this dysbiosis, various methods have been examined to alter the composition of the intestinal microflora, including the administration of antibiotics and introduction of probiotic species. This article summarizes studies evaluating the efficacy of antibiotics and probiotics in the induction and maintenance of remission of ulcerative colitis, Crohn's disease, and pouchitis. |
| doi_str_mv | 10.1007/s11894-006-0039-z |
| format | Article |
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| ispartof | Current gastroenterology reports, 2006-12, Vol.8 (6), p.486-498 |
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| language | eng |
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| source | MEDLINE; ProQuest Central (Alumni Edition); ProQuest Central UK/Ireland; SpringerLink Journals - AutoHoldings; ProQuest Central |
| subjects | Anti-Bacterial Agents - therapeutic use Antibiotics Humans Inflammatory Bowel Diseases - drug therapy Probiotics - therapeutic use Remission Induction - methods Treatment Outcome |
| title | The role of antibiotic and probiotic therapies in current and future management of inflammatory bowel disease |
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