Integrated PET-CT for the characterization of adrenal gland lesions in cancer patients: diagnostic efficacy and interpretation pitfalls
Integrated fluorine-18 fluorodeoxyglucose positron emission tomography (PET)-computed tomography (CT) for adrenal gland imaging in cancer patients allows early detection and accurate localization of adrenal lesions and differentiation of metastatic nodules from benign lesions, thereby facilitating t...
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Veröffentlicht in: | Radiographics 2006-11, Vol.26 (6), p.1811-1824 |
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container_title | Radiographics |
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creator | Chong, Semin Lee, Kyung Soo Kim, Ha Young Kim, Yoon Kyung Kim, Byung-Tae Chung, Myung Jin Yi, Chin A Kwon, Ghee Young |
description | Integrated fluorine-18 fluorodeoxyglucose positron emission tomography (PET)-computed tomography (CT) for adrenal gland imaging in cancer patients allows early detection and accurate localization of adrenal lesions and differentiation of metastatic nodules from benign lesions, thereby facilitating treatment planning. However, false-positive findings are encountered at integrated PET-CT in approximately 5% of adrenal lesions identified as positive at PET, including adrenal adenomas, adrenal endothelial cysts, and inflammatory and infectious lesions. Moreover, false-negative findings may be seen in adrenal metastatic lesions with hemorrhage or necrosis, small-sized ( |
doi_str_mv | 10.1148/rg.266065057 |
format | Article |
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However, false-positive findings are encountered at integrated PET-CT in approximately 5% of adrenal lesions identified as positive at PET, including adrenal adenomas, adrenal endothelial cysts, and inflammatory and infectious lesions. Moreover, false-negative findings may be seen in adrenal metastatic lesions with hemorrhage or necrosis, small-sized (<10-mm) metastatic nodules, and metastases from pulmonary bronchioloalveolar carcinoma or carcinoid tumors. 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However, false-positive findings are encountered at integrated PET-CT in approximately 5% of adrenal lesions identified as positive at PET, including adrenal adenomas, adrenal endothelial cysts, and inflammatory and infectious lesions. Moreover, false-negative findings may be seen in adrenal metastatic lesions with hemorrhage or necrosis, small-sized (<10-mm) metastatic nodules, and metastases from pulmonary bronchioloalveolar carcinoma or carcinoid tumors. An awareness of the potential pitfalls of integrated PET-CT enhances the diagnostic efficacy of this modality by allowing differentiation of metastatic adrenal lesions from other abnormalities.</description><subject>Adrenal Gland Neoplasms - diagnosis</subject><subject>Diagnostic Errors - prevention & control</subject><subject>Humans</subject><subject>Image Enhancement - methods</subject><subject>Positron-Emission Tomography - methods</subject><subject>Practice Guidelines as Topic</subject><subject>Practice Patterns, Physicians</subject><subject>Subtraction Technique</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>0271-5333</issn><issn>1527-1323</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkT9P5DAQxS10CPaAjvrk6irCefwvWbrTCg4kpKNY6sixx8Eom-RsbwFfgK-N0a64kmL0pNFv3ujpEXIO7BJANr9if8m1ZloxVR-QBSheVyC4-EYWjNdQKSHEMfme0jNjIFWjj8gx1MA4U3xB3u7GjH00GR19uF5XqzX1U6T5Cal9MtHYjDG8mhymkU6eGhdxNAPtBzM6OmAq-0TDSK0ZLUY6FxLHnK6oC6Yfp5SDpeh9sMa-0I-bUP7FOWLeec4hezMM6ZQcFk14ttcT8nhzvV7dVvd__9ytft9XVnKZK7CNANUsvXS11KrTXnPnG6UFiM4L4xRHW6uONRyk5dx1GuplGV9rxYUTJ-TnzneO078tptxuQrI4lDw4bVOrG5BCaf4lCEtZWM4KeLEDbZxSiujbOYaNiS8tsPajoTb27WdDBf-x9912G3T_4X0l4h3OIIzU</recordid><startdate>200611</startdate><enddate>200611</enddate><creator>Chong, Semin</creator><creator>Lee, Kyung Soo</creator><creator>Kim, Ha Young</creator><creator>Kim, Yoon Kyung</creator><creator>Kim, Byung-Tae</creator><creator>Chung, Myung Jin</creator><creator>Yi, Chin A</creator><creator>Kwon, Ghee Young</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>200611</creationdate><title>Integrated PET-CT for the characterization of adrenal gland lesions in cancer patients: diagnostic efficacy and interpretation pitfalls</title><author>Chong, Semin ; Lee, Kyung Soo ; Kim, Ha Young ; Kim, Yoon Kyung ; Kim, Byung-Tae ; Chung, Myung Jin ; Yi, Chin A ; Kwon, Ghee Young</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c424t-1c831589f4d7465b6f62df856313bf3ad52ec75b08214c22db6179617f76523d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adrenal Gland Neoplasms - diagnosis</topic><topic>Diagnostic Errors - prevention & control</topic><topic>Humans</topic><topic>Image Enhancement - methods</topic><topic>Positron-Emission Tomography - methods</topic><topic>Practice Guidelines as Topic</topic><topic>Practice Patterns, Physicians</topic><topic>Subtraction Technique</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chong, Semin</creatorcontrib><creatorcontrib>Lee, Kyung Soo</creatorcontrib><creatorcontrib>Kim, Ha Young</creatorcontrib><creatorcontrib>Kim, Yoon Kyung</creatorcontrib><creatorcontrib>Kim, Byung-Tae</creatorcontrib><creatorcontrib>Chung, Myung Jin</creatorcontrib><creatorcontrib>Yi, Chin A</creatorcontrib><creatorcontrib>Kwon, Ghee Young</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Radiographics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chong, Semin</au><au>Lee, Kyung Soo</au><au>Kim, Ha Young</au><au>Kim, Yoon Kyung</au><au>Kim, Byung-Tae</au><au>Chung, Myung Jin</au><au>Yi, Chin A</au><au>Kwon, Ghee Young</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Integrated PET-CT for the characterization of adrenal gland lesions in cancer patients: diagnostic efficacy and interpretation pitfalls</atitle><jtitle>Radiographics</jtitle><addtitle>Radiographics</addtitle><date>2006-11</date><risdate>2006</risdate><volume>26</volume><issue>6</issue><spage>1811</spage><epage>1824</epage><pages>1811-1824</pages><issn>0271-5333</issn><eissn>1527-1323</eissn><abstract>Integrated fluorine-18 fluorodeoxyglucose positron emission tomography (PET)-computed tomography (CT) for adrenal gland imaging in cancer patients allows early detection and accurate localization of adrenal lesions and differentiation of metastatic nodules from benign lesions, thereby facilitating treatment planning. 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subjects | Adrenal Gland Neoplasms - diagnosis Diagnostic Errors - prevention & control Humans Image Enhancement - methods Positron-Emission Tomography - methods Practice Guidelines as Topic Practice Patterns, Physicians Subtraction Technique Tomography, X-Ray Computed - methods |
title | Integrated PET-CT for the characterization of adrenal gland lesions in cancer patients: diagnostic efficacy and interpretation pitfalls |
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