A1298C polymorphism of the MTHFR gene and neural tube defects in the state of Yucatan, Mexico

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) of the folate metabolism pathway is a candidate gene for neural tube defects (NTDs). Frequency of the second common polymorphism, A1298C, in the MTHFR gene is not well known in Mexico. Conflicting results exist regarding the association of A129...

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Veröffentlicht in:	Birth defects research. A Clinical and molecular teratology 2007-08, Vol.79 (8), p.622-626
Hauptverfasser:	Gonzalez-Herrera, Lizbeth, Castillo-Zapata, Ileana, Garcia-Escalante, Guadalupe, Pinto-Escalante, Doris
Format:	Artikel
Sprache:	eng
Schlagworte:	A1298C Case-Control Studies Female Gene Frequency Genotype Humans Infant, Newborn Male Methylenetetrahydrofolate Reductase (NADPH2) - genetics Methylenetetrahydrofolate Reductase (NADPH2) - metabolism Mexico - epidemiology MTHFR Neural Tube Defects - enzymology Neural Tube Defects - epidemiology Neural Tube Defects - genetics NTD polymorphism Polymorphism, Genetic Yucatan
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