Muscarinic Receptors Mediate Stimulation of Human Lung Fibroblast Proliferation

Airway remodeling is a structural alteration associated with chronic inflammatory and obstructive airway diseases, wherein fibroblasts are crucially involved. The present study investigates whether lung fibroblast proliferation is influenced by muscarinic mechanisms. For this purpose, expression of...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2006-12, Vol.35 (6), p.621-627
Hauptverfasser:	Matthiesen, Sonja, Bahulayan, Amit, Kempkens, Susanne, Haag, Susanne, Fuhrmann, Margarita, Stichnote, Christine, Juergens, Uwe R, Racke, Kurt
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cell Proliferation Dose-Response Relationship, Drug Fibroblasts - metabolism Humans Lung - cytology Muscarinic Agonists - pharmacology Muscarinic Antagonists - pharmacology Receptor, Muscarinic M2 - drug effects Receptor, Muscarinic M2 - metabolism Receptors, Muscarinic - genetics Receptors, Muscarinic - metabolism RNA, Messenger - metabolism
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