Rosenthal Fiber Encephalopathy in a Dog Resembling Alexander Disease in Humans

A young male Bernese mountain dog presented with neurologic abnormalities consisting of nonambulatory tetraparesis, generalized tremors, and depressed mental status. At necropsy only a mild enlargement of the lateral ventricles was seen. The histologic examination revealed the presence of eosinophil...

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Veröffentlicht in:	Veterinary pathology 2006-11, Vol.43 (6), p.1025-1028
Hauptverfasser:	Alemañ, N, Marcaccini, A, Espino, L, Bermúdez, R, Nieto, J.M, López-Peña, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alexander Disease alpha-Crystallin B Chain - metabolism Animals astrocytes Bernese mountain dog Central Nervous System - pathology central nervous system diseases dog breeds Dogs encephalopathy eosinophils genetic disorders glial fibrillary acidic protein histopathology human diseases Humans immunohistochemistry Male Neurodegenerative Diseases - diagnosis Neurodegenerative Diseases - pathology Neurodegenerative Diseases - veterinary proteins Rosenthal fibers
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