A quantitative observation and imaging of single tumor cell migration and deformation using a multi-gap microfluidic device representing the blood vessel

A microfluidic device was developed for quantifying the migratory and deformability capabilities of a single tumor cell using direct imaging. It was fabricated using photolithography and is made of polydimethysiloxane. Chemotaxis approach was used for directing cell movement, using 10 μm microgaps t...

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Veröffentlicht in:	Microvascular research 2006-11, Vol.72 (3), p.153-160
Hauptverfasser:	Chaw, K.C., Manimaran, M., Tay, Francis E.H., Swaminathan, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Cell Line, Tumor Cell Movement - physiology Cell Shape - physiology Chemotaxis Chemotaxis - physiology Deformation HeLa Cells Humans Metastasis Microfluidic Analytical Techniques - instrumentation Microfluidic Analytical Techniques - methods Microfluidics Migration Neoplasms - blood supply Neoplasms - pathology Photolithography Reproducibility of Results
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