Tau phosphorylation in the mouse brain during aversive conditioning

Stress response is intimately involved in memory formation. Stress has been shown to cause reversible Alzheimer-like tau phosphorylation in the brain of experimental animals, but it is not known whether tau phoshorylation takes place during memory acquisition. As an initial investigation we chose co...

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Veröffentlicht in:	Neurochemistry international 2007-07, Vol.51 (2), p.200-208
Hauptverfasser:	Fujio, Junko, Hosono, Hiroaki, Ishiguro, Koichi, Ikegami, Shiro, Fujita, Shinobu C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer Disease - physiopathology Alzheimer's disease Animals Avoidance Learning - physiology Binding Sites - physiology Biological and medical sciences Brain - metabolism Brain - physiopathology Conditioning (Psychology) - physiology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Electroshock Fear - physiology Footshock Fundamental and applied biological sciences. Psychology Glycogen Synthase Kinase 3 - metabolism Glycogen Synthase Kinase 3 beta Hippocampus Hippocampus - metabolism Hippocampus - physiopathology Learning Male Medical sciences Memory Disorders - etiology Memory Disorders - metabolism Memory Disorders - physiopathology Mice Mice, Inbred C57BL Neurology Phosphorylation Protein-Serine-Threonine Kinases - metabolism Stress, Psychological - complications Stress, Psychological - metabolism Stress, Psychological - physiopathology Tau phosphorylation tau Proteins - metabolism Up-Regulation - physiology Vertebrates: nervous system and sense organs
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