Differential dynamic of action on cortical and subcortical structures of anesthetic agents during induction of anesthesia

Dynamic action of anesthetic agents was compared at cortical and subcortical levels during induction of anesthesia. Unconsciousness involved the cortical brain but suppression of movement in response to noxious stimuli was mediated through subcortical structures. Twenty-five patients with Parkinson...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2007-08, Vol.107 (2), p.202-212
Hauptverfasser:	VELLY, Lionel J, REY, Marc F, BRUDER, Nicolas J, GOUVITSOS, Francois A, WITJAS, Tatiana, REGIS, Jean Marie, PERAGUT, Jean Claude, GOUIN, Francois M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia Anesthesia - methods Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics - pharmacology Biological and medical sciences Cerebral Cortex - drug effects Consciousness - drug effects Deep Brain Stimulation - methods Dose-Response Relationship, Drug Electrodes, Implanted Electroencephalography - drug effects Electroencephalography - methods Female Humans Laryngoscopy - methods Male Medical sciences Methyl Ethers - pharmacology Middle Aged Monitoring, Intraoperative - methods Movement - drug effects Parkinson Disease - therapy Predictive Value of Tests Propofol - pharmacology Prospective Studies ROC Curve Subthalamic Nucleus - drug effects
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